Myasthenic crisis occurs in approximately 15%–20% of patients with MG usually within the first 2 to 3 y of the disease course[1], which involves respiratory muscles, resulting in cough weakness and dyspnea, which cannot maintain normal ventilation function and must be assisted by ventilators [1]. Early assessment of respiratory muscle function in MG patients can provide evidence for the risk of myasthenic crisis. The diaphragm, as the main respiratory muscle, separates the chest cavity from the abdominal cavity and is closely related to respiratory function. However, the literature on the function of the diaphragm has not been effectively integrated in the past. This article will summarize the influencing factors of myasthenia gravis antibody, clinical classification, mechanism, manifestation, examination and diagnosis methods of diaphragmatic dysfunction, so as to provide a certain reference for further research and clinical application of respiratory function in MG patients. |