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| 基于ADNI中PET/CT的阿尔茨海默病致病机制及诊断的最新研究 |
| Recent advancements in research of PET/CT in Alzheimer"s disease based on ADNI database |
| 投稿时间：2023-10-27 修订日期：2023-10-28 |
| DOI： |
| 中文关键词: 阿尔茨海默病、ADNI、正电子发射断层显像、Aβ级联假说、深度学习 |
| 英文关键词: Alzheimer"s disease, ADNI, PET, Aβ cascade hypothesis, Deep Learning. |
| 基金项目:基于功能及代谢影像学技术探讨PD-MCI患者双任务下异常步态的神经机制研究（202203021221255）（HUG-MHHZHTP-XJWWW） |
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| 中文摘要: |
| 阿尔茨海默病(Alzheimer"s disease, AD)已成为中国65岁及以上人群的第四大死因,PET/CT在AD的临床诊断和致病机制研究中发挥了重要的作用,阿尔茨海默病神经影像学倡议(Alzheimer’s Disease Neuroimaging Initiative, ADNI)中的PET/CT联合数字技术为跟踪患者认知变化轨迹、提升临床诊断精度提供重要的科学支撑。本文重点综述了近3年ADNI中的PET/CT在探索AD病理进展模式及早期诊断的研究进展。 |
| 英文摘要: |
| Alzheimer"s disease (AD) has become the fourth leading cause of death among people aged 65 and above in China. The Positron emission tomography (PET) plays an important role in clinical diagnosis and exploration of the pathogenesis of AD, and PET/CT which from the Alzheimer"s Disease Neuroimaging Initiative (ADNI) combined with digital technology provides a significant scientific support to track the trajectory of cognitive changes of patients and improve the accuracy of clinical diagnosis. |
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