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高原肠道菌群与动脉粥样硬化性缺血性脑卒中的相关性研究 |
Progress in the Study of Intestinal Flora and Atherosclerotic Ischemic Stroke in Highlands |
投稿时间:2023-10-24 修订日期:2023-10-24 |
DOI: |
中文关键词: 高原 肠道菌群 缺血性脑卒中 |
英文关键词: Plateau intestinal flora ischemic stroke |
基金项目:青海省科技厅项目(2022-ZJ-761); |
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中文摘要: |
肠道微生物组是人体内最大的微生物库,在神经发育、衰老和脑部疾病中发挥着重要作用。近年来,肠道菌群越来越受到世界学者的关注,其与缺血性脑卒中的关系也成为脑卒中研究者的热门研究课题。在正常情况下,肠道微生物群与人体和外部环境保持平衡状态,然而在高原地区,大多数人因缺氧发生消化功能紊乱导致细菌移位和肠道微生物群失衡。本文就动脉粥样硬化性缺血性脑卒中与高原肠道菌群的相关性研究做一综述,同时对其治疗前景进行展望。 |
英文摘要: |
The gut microbiome is the largest microbial reservoir in the body and plays an important role in neurodevelopment, aging and brain
diseases such as ischemic stroke. In recent years, the gut flora has
received increasing attention from scholars worldwide, and its relationship with ischemic stroke has become a popular research topic among stroke researchers. Under normal conditions, the gut microbiota is in balance with the body and the external environment; however, in highland areas, most people experience digestive dysfunction due to hypoxia resulting in bacterial translocation and imbalance of the gut microbiota. In this paper, we review the research on the correlation between atherosclerotic ischemic stroke and the gut flora in plateau, and also provide an outlook on its treatment. |
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