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| 童年创伤与酒精使用障碍的机制研究进展 |
| Research Progress on the Mechanisms of Adverse Childhood Experience and Alcohol Use Disorder |
| 投稿时间：2025-07-21 修订日期：2025-07-21 |
| DOI： |
| 中文关键词: 童年创伤 酒精使用障碍 神经生物学机制 酒精 |
| 英文关键词: Adverse childhood experience, alcohol use disorder, neurobiological mechanism, Alcohol |
| 基金项目:2023 年度上海市健康科普人才能力提升专项 |
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| 中文摘要: |
| 广泛研究表明，童年创伤是导致酒精使用障碍发生的一个重要危险因素。本文从生理、心理和社会三个维度探讨童年创伤与酒精使用障碍的相关机制。生理层面涉及内分泌系统、大脑发育的改变等；心理层面涉及情绪调节障碍、应对机制不良等；社会层面涉及家庭环境、社会支持系统缺乏等。本综述旨在系统探讨童年创伤与酒精使用障碍之间的相关性，并分析其作用机制，为医护人员有针对性地为临床干预措施的制定提供依据。 |
| 英文摘要: |
| Extensive research has shown that Adverse childhood experience is a significant risk factor for the development of alcohol use disorders. we will explore in depth how Adverse childhood experience affects an individual's alcohol use behavior from three dimensions: physiological, psychological, and social. The physiological dimension involves changes in the endocrine system, brain development, etc.; the psychological dimension involves impaired emotion regulation, poor coping mechanisms, etc.; and the social dimension involves the family environment, lack of social support system, etc. The review is aimed to systematically explore the correlation between Adverse childhood experience and alcohol use disorders and to analyze the mechanism of action, so as to provide a basis for healthcare professionals to develop targeted clinical interventions. |
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