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| 中药复方治疗阿尔兹海默病的实验研究进展 |
| Experimental Research Progress in the Treatment of Alzheimer's Disease with Traditional Chinese Medicine Compound Formulas |
| 投稿时间：2025-05-13 修订日期：2025-05-13 |
| DOI： |
| 中文关键词: 中药复方 阿尔兹海默病 神经退行性疾病 |
| 英文关键词: Traditional Chinese medicine compound formula Alzheimer's disease Neurodegenerative disease |
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| 中文摘要: |
| 阿尔兹海默病（AD）是一种慢性进行性神经退行性疾病，主要表现为记忆障碍、认知功能下降及人格改变，占老年期痴呆病例的60%至80%。全球AD患者数量已超过5000万，预计到2050年将突破1.52亿，给患者家庭和社会带来沉重负担。AD的发病机制尚未完全阐明，现有药物虽可缓解部分症状，但无法阻止疾病进展。而中药复方在治疗 AD 上有巨大的潜力和独特的优势。本文中药复方治疗AD的实验研究进展进行综述，为AD的临床治疗提供了思路和理论依据。 |
| 英文摘要: |
| Abstract: Alzheimer's disease (AD) is a chronic progressive neurodegenerative disorder characterized by memory impairment, cognitive decline, and personality changes, accounting for 60% to 80% of senile dementia cases. The global number of AD patients has exceeded 50 million and is projected to surpass 152 million by 2050, imposing a heavy burden on patients' families and society. The pathogenesis of AD remains incompletely understood, and while existing medications can alleviate some symptoms, they fail to halt disease progression. Traditional Chinese medicine (TCM) compounds exhibit significant potential and unique advantages in treating AD. This article reviews experimental research advancements in TCM formulas for AD treatment, providing insights and theoretical foundations for clinical management of the disease. |
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