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| 针刺治疗功能性消化不良焦虑抑郁情绪：一项系统评价和Meta分析 |
| Acupuncture for the Treatment of Anxiety and Depression in Functional Dyspepsia: A Systematic Review and Meta-Analysis |
| 投稿时间：2025-02-20 修订日期：2025-02-20 |
| DOI： |
| 中文关键词: 针刺 功能性消化不良 餐后不适综合征 上腹痛综合征 焦虑抑郁情绪 Meta分析 |
| 英文关键词: Acupuncture Functional dyspepsia Postprandial distress syndrome Epigastric pain syndrome Anxiety and depressive mood Meta-analysis |
| 基金项目:黑龙江省博士后科研启动金资助LBH-Q21183；黑龙江中医药大学校科研基金资助2019MS21；黑龙江省博士后基金LBH-Z21216 |
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| 中文摘要: |
| 目的：采用Meta分析评估针刺治疗功能性消化不良焦虑抑郁情绪的有效性。方法：检索自建库起至2024年1月中国期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang）、维普资讯中文期刊服务平台（VIP）、中国生物医学文献服务系统（SinoMed）及PubMed、Web of Science、Embase 7个数据库收录的与针刺治疗功能性消化不良焦虑抑郁情绪相关的随机对照研究文献。运用Revman 5.3、Stata 17.0对相关结局指标进行Meta分析。结果：在纳入的随机对照研究中，包括832名功能性消化不良患者(治疗组416例，对照组416例)。Meta分析结果得出：与对照组相比，针刺能够改善患者的SAS[MD=-0.55,95%CI(-1.01,-0.10)]、SDS[MD=-1.18,95%CI(-1.84,-0.52)]、HAMA[MD=-4.73,95%CI(-11.59,2.12)]、HAMD[MD=-4.35,95%CI(-9.15,0.44)]、HADS[MD=-3.01,95%CI(-4.73,-1.29)]、消化不良症状积分[MD=-1.55,95%CI(-2.04,-1.07)]、总有效率[MD=2.62,95%CI(1.70,4.01)]。结论：针刺对于功能性消化不良患者的症状及焦虑抑郁情绪均具有改善作用，但证据等级偏低，后续需要纳入更高质量的随机对照试验以进一步验证结果。 |
| 英文摘要: |
| Objective: To assess the effectiveness of acupuncture in treating anxiety and depression in functional dyspepsia (FD) using Meta-analysis. Methods: We searched China National Knowledge Infrastructure (CNKI), Wanfang Database (Wanfang), VIP Database (VIP), Chinese Biomedical Literature Service System (SinoMed), PubMed, Web of Science, and Embase, from the establishment of the database to January, 2024, to identify randomized controlled studies of acupuncture treatment for functional dyspepsia, anxiety and depression. Literature of randomized controlled studies related to acupuncture for functional dyspepsia anxiety and depressed mood. Meta-analysis of relevant outcome indicators was performed using Revman 5.3 and Stata 17.0. Results: In the included randomized controlled trials, 832 patients with functional dyspepsia were included (416 patients in the treatment group and 416 patients in the control group). Meta-analysis results concluded that compared to control group, acupuncture improved patients' SAS [MD=-0.55,95%CI(-1.01,-0.10)], SDS [MD=-1.18,95%CI(-1.84,-0.52)], HAMA [MD=-4.73,95%CI(-11.59,2.12)], HAMD [MD=-4.35,95%CI(-9.15,0.44)], HADS [MD=-3.01,95%CI(-4.73,-1.29)], dyspepsia symptom score [MD=-1.55,95%CI(-2.04,-1.07)], and total effective rate [MD=2.62,95%CI(1.70,4.01)]. Conclusion: Acupuncture has an ameliorative effect on both symptoms and anxiety and depression in patients with functional dyspepsia, but the level of evidence is low, and higher-quality randomized controlled trials need to be included to further validate the results. |
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