| 陈琳，龚秋文，戴玮讷，侯景明.镜像神经元疗法联合交流效果促进法有效治疗非急性期脑卒中后非流畅性失语症[J].神经损伤功能重建,2025,(2):79-83 |
| 镜像神经元疗法联合交流效果促进法有效治疗非急性期脑卒中后非流畅性失语症 |
| Mirror Neuron System Based Therapy Combined with Promoting Aphasics Communication Isan Effective Treatment for Non-Fluent Aphasia in Non-Acute Phase after Stroke |
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| DOI： |
| 中文关键词: 镜像神经元疗法 交流效果促进法 亚急性期 非流畅性失语症 脑卒中 |
| 英文关键词: mirror neuron system based therapy promoting aphasics communication effectiveness subacute phase non-fluent aphasia stroke |
| 基金项目: |
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| 摘要点击次数: 304 |
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| 中文摘要: |
| 目的：探讨镜像神经元疗法（MNST）仪器训练与交流效果促进法（PACE）人工一对一言语康复模式
对亚急性期脑卒中后非流畅性失语症患者言语功能的康复疗效。方法：纳入2022年3月～2023年6月在
我院康复医学科治疗的亚急性期脑卒中非流畅性失语症患者60例，随机分为PACE组、MNST组和联合
组，各20例。MNST组接受MNST治疗30 min，PACE组接受PACE治疗30 min，联合组分别接受MNST治
疗和PACE治疗各15 min；治疗频率和时长均为1 次/d，5 d/周，连续治疗4周。收集、比较所有患者治疗前、
治疗4周后西方失语症成套测验（WAB）和波士顿诊断性失语症检查法（BDAE）的评估结果。结果：PACE
脱失1例。治疗前，3组WAB的各项评分差异无统计学意义（P＞0.05），BDAE分级的差异无统计学意义
（P＞0.05）。治疗4周后，组内比较：3组WAB的自发言语、听理解、复述、命名、AQ均较同组治疗前显著改
善（P＜0.01）；组间比较：①联合组与PACE组比较，联合组自发言语评分、复述评分、命名评分、AQ评分优
于PACE组（均P＜0.05）；②联合组与MNST组比较，联合组复述评分、命名评分、AQ评分优于MNST组
（均P＜0.05）；③MNST组与PACE组比较，MNST组复述评分高于PACE组（P＜0.05）；其他组间评分无显
著差异（P＞0.05）。 治疗4周后，3组的BDAE分级均较治疗前有所提高（P＜0.05）。联合组BDAE分级优
于PACE组和MNST组（P＜0.05），PACE组和MNST组比较无显著性差异（P＞0.05）。结论：对于亚急性期
脑卒中非流畅性失语症患者，MNST机器训练在复述能力提升上效果优于以PACE治疗为主的一对一人工
训练，两者联合治疗的效果优于单一MNST治疗和单一PACE治疗。 |
| 英文摘要: |
| To explore the rehabilitation efficacy of Mirror Neuron System Based Therapy(MNST)
instrument training combined with the Promotion of Communication Effectiveness Method (PACE) one-on-one
speech rehabilitation model on post-acute phase stroke patients with non-fluent aphasia. Methods: Sixty patients with non-fluent aphasia after sub-acute phase stroke treated in our hospital’s department of rehabilitation
medicine from March 2022 to June 2023 were randomly divided into PACE group, MNST group, and combined
group, with 20 cases in each group. The MNST group received MNST treatment for 30 minutes, the PACE
group received PACE treatment for 30 minutes, and the combined group received both MNST and PACE treatments for 15 minutes each; the treatment frequency and duration were once per day, five days per week, for four
consecutive weeks. The Western Aphasia Battery (WAB) and Boston Diagnostic Aphasia Examination (BDAE)
assessment results before and after four weeks of treatment were collected and compared among all patients.
Results: One case dropped out from the PACE group. Before treatment, there were no significant differences
in WAB scores or BDAE grading among the three groups (P>0.05). After four weeks of treatment, intra-group
comparison showed that spontaneous speech, auditory comprehension, repetition, naming, and AQ in the WAB
significantly improved in all three groups compared to pre-treatment (P<0.01); inter-group comparison revealed: (1) Compared to the PACE group, the combined group had better scores in spontaneous speech, repetition, naming, and AQ (all P<0.05); (2) Compared to the MNST group, the combined group had better scores in
repetition, naming, and AQ (all P<0.05); (3) The MNST group had higher repetition scores than the PACE group (P<0.05); other inter-group scores showed no significant differences (P>0.05). After four weeks of treatment, the BDAE grading improved in all three
groups compared to pre-treatment (P<0.05). The combined group had a better BDAE grading than both the PACE and MNST groups (P<
0.05), while there was no significant difference between the PACE and MNST groups (P>0.05). Conclusion: For patients with non-fluent
aphasia after sub-acute phase stroke, MNST machine training is more effective than PACE-based one-on-one manual training in improving repetition ability. The combination of the two treatments has a better effect than either MNST alone or PACE alone. |
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