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| 多种干预措施治疗帕金森后吞咽障碍的网状meta分析 |
| A Network meta-analysis of multiple interventions for the treatment of dysphagia after Parkinson 's disease |
| 投稿时间：2024-12-20 修订日期：2024-12-20 |
| DOI： |
| 中文关键词: 帕金森 吞咽障碍 干预措施 网状Meta分析 |
| 英文关键词: Parkinson dysphagia interventions Network Meta-analysis |
| 基金项目:1.山东中医药大学科研创新团队基金资助项目(220316）；2.山东省老年医学学会基金(LKJGG2021Z018)；3.山东省卫生健康委员会基金（2018WS205）；4.山东省高等学校科技计划项目（J14LK08）。 |
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| 中文摘要: |
| 【摘要】目的：系统评价多种干预措施对帕金森患者吞咽功能的改善效果。方法：检索CNKI, Wanfang, VIP, CBM, PubMed, Medline和Web of science数据库，搜集关于不同治疗方法治疗帕金森患者吞咽障碍的RCTs，时段为建库至2024年3月15日。利用RevMan 5.4.1软件评估纳入研究的质量，Stata 17.0软件进行网状Meta分析。结果：纳入研究29篇，1870位患者，涉及到针刺、电刺激、呼吸训练等13种治疗方法。网状Meta分析结果显示，在提高帕金森临床有效率及PAS方面，训练效果最好的是呼吸训练；提高SSA、洼田饮水评分方面，重复经颅磁刺激与电刺激效果最好。结论：现有证据表明，呼吸训练成为治疗帕金森吞咽障碍最佳干预方案的可能性最大，重复经颅磁刺激与电刺激也具有一定优势，但临床应用中仍然需要综合考虑不同病人的实际情况。 |
| 英文摘要: |
| [Abstract] Objective: To systematically evaluate the effect of various interventions on the improvement of swallowing function in patients with Parkinson 's disease. Methods: CNKI, Wanfang, VIP, CBM, PubMed, Medline and Web of science databases were searched to collect RCTs on different treatment methods for dysphagia in Parkinson 's patients from inception to March 15,2024. RevMan 5.4.1 software was used to evaluate the quality of the included studies, and Stata 17.0 software was used for network meta-analysis. Results: A total of 29 studies involving 1870 patients were included, involving 13 treatment methods such as acupuncture, electrical stimulation, and respiratory training. The results of network meta-analysis showed that the best training effect was respiratory training in improving the clinical efficiency and PAS of Parkinson 's disease. In terms of improving SSA and Kubota drinking water scores, repetitive transcranial magnetic stimulation and electrical stimulation have the best effect.Conclusion: The existing evidence shows that respiratory training is the most likely to be the best intervention for Parkinson 's dysphagia. Repetitive transcranial magnetic stimulation and electrical stimulation also have certain advantages, but the actual situation of different patients still needs to be considered in clinical application. |
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