| To explore the application of task-oriented training combined with brain-computer interface (BCI) in the rehabilitation therapy of lower limb motor function in post-stroke hemiplegia (PSH) patients. Methods: From May 2023 to January 2024, 92 elderly PSH patients admitted to our hospital were randomly assigned into a control group (receiving task-oriented training, n=46) and a combination therapy group (receiving task oriented training+BCI, n=46). The lower limb motor function, three-dimensional gait indicators, manual muscle test (MMT), body balance ability, nerve factors, and daily living ability of the two groups were compared before (T0) and after (T1) therapy. Results Compared with T0, the Fugl-Meyer Assessment (FMA) score, MMT score, Berg Balance Scale (BBS) score, Modified Barthel Index (MBI) score, and three-dimensional gait indicators (step speed, step frequency, stride ratio) in both groups were obviously increased at T1, and the combination therapy group showed a more obvious increase compared to the control group (P<0.05). Compared with T0, the serum levels of soluble protein-100β (S100β) and neuron specific enolase (NSE) were obviously reduced in both groups at T1, and the decrease was more obvious in the combination therapy group compared with the control group (P<0.05). Conclusion: Task-oriented training combined with BCI therapy can obviously improve the lower limb motor function and body balance of patients with PSH, improve muscle strength, adjust nerve factors, further enhance daily living abilities, and promote physical recovery. |