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| 星形胶质细胞—神经元在抑郁症脑葡萄糖代谢中的研究进展 |
| RESEARCH PROGRESS OF ASTROCYTES-NEURONS IN CEREBRAL GLUCOSE METABOLISM OF DEPRESSION |
| 投稿时间：2024-09-26 修订日期：2024-09-26 |
| DOI： |
| 中文关键词: 刘相玉，费加明 |
| 英文关键词: LIU Xiangyu, FEI jiaming |
| 基金项目:2023年淮南师范学院校级自然科学科研项目（2023XJYB037）；2024年淮南师范学院校级重点教育教学改革研究项目(2024hsjyxm26)；2024年安徽省教育科学研究政策咨询项目（JKZ24003）。 |
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| 中文摘要: |
| 随着对抑郁症的研究日益深入，越来越多的证据表明，抑郁症的发生与发展和脑部能量代谢有着密切的联系。通过对脑部能量代谢的研究以及对脑部各个细胞特点的分析，该文聚焦于星形胶质细胞和神经元之间代谢互作，把星形胶质细胞—神经元作为一个能量代谢整体对抑郁症的影响进行综述，重点关注脑葡萄糖代谢及代谢中间产物对神经系统结构和功能的影响，以期为治疗抑郁症寻找新机制，为研究抑郁症提供新角度。 |
| 英文摘要: |
| With the deepening of research on depression, more and more evidences show that the occurrence and development of depression are closely related to brain energy metabolism. By studying the energy metabolism of the brain and analysing the characteristics of individual cells in the brain, we focus on the metabolic interactions between astrocytes and neurons, and review the effects of astrocyte-neuron as an energy metabolism whole on depression. We focus on the effects of cerebral glucose metabolism and metabolic intermediates on the structure and function of the nervous system, with the aim of searching for new mechanisms for the treatment of depression and providing new perspectives for the study of depression. |
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