| 冯露叶
，唐炳舜
，金一兰
，汤继芹，.针刺联合重复经颅磁刺激治疗脑卒中后抑郁疗效的Meta分析[J].神经损伤功能重建,2024,(7):397-401 |
| 针刺联合重复经颅磁刺激治疗脑卒中后抑郁疗效的Meta分析 |
| A Meta-analysis of Efficacy of Acupuncture Combined with Repetitive Transcranial MagneticStimulation for Post-Stroke Depression |
| |
| DOI： |
| 中文关键词: 脑卒中后抑郁 针刺 重复经颅磁刺激 Meta分析 |
| 英文关键词: post-stroke depression acupuncture repetitive transcranial magnetic stimulation Meta-analysis |
| 基金项目:山东省老年医学学
会科技发展计划项
目（针刺与重复经
颅磁刺激治疗老年
轻度抑郁症的循证
研究，No. LKJGG2
021Z018）；山东省
中医药科技发展计
划项目（艾灸结合
疏肝调神针法治疗
脑卒中后抑郁症的
临 床 研 究 ，No.
2015-029）；教育部
产学合作协同育人
项目（言语治疗学
课程创新创业教育
研究——以《言语
康复产品开发》为
例，No. 202002137
071） |
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| 中文摘要: |
| 目的：系统评价针刺联合重复经颅磁刺激治疗脑卒中后抑郁的临床疗效。方法：检索 CNKI、
Sinomed、Wanfang、VIP、PubMed、Cochrane Library、Web of science、EMBASE 数据库中关于针刺联合重复
经颅磁刺激治疗脑卒中后抑郁的临床随机对照试验，检索时间自建库起至2023年7月。通过Cochrane偏
倚风险评估工具对纳入文献进行偏倚分析和质量评价，Revman5.4软件进行Meta分析以及采用GRADE软
件对结局指标进行证据质量评价。结果：纳入10篇文献，共622例受试者。针刺联合重复经颅磁刺激在改
善卒中后抑郁患者的临床疗效[RR=1.14，95%CI(1.06，1.24)，P=0.0009]，汉密尔顿抑郁量表（Hamilton depression scale，HAMD）评分[MD=－3.75, 95%CI(－5.86, －1.64), P=0.0005]，匹兹堡睡眠质量指数（Pittsburgh sleep quality index，PSQI）等评分方面均优于对照组。结局指标质量评价结果显示临床疗效为中级，
HAMD评分为低级，PSQI评分为极低级。结论：针刺联合重复经颅磁刺激在改善脑卒中后患者的抑郁情
况方面具有显著优势。 |
| 英文摘要: |
| To systematically evaluate the clinical efficacy of acupuncture combined with repetitive
transcranial magnetic stimulation (rTMS) in treatment of post-stroke depression. Methods: A systematic search
was conducted in databases of CNKI, CBM, Wanfang, VIP, PubMed, Web of Science, Cochrane Library and
EMBASE for randomized controlled trials (RCTs) of acupuncture combined with rTMS in the treatment of
post-stroke depression from their inception to July 2023. The Cochrane risk of bias assessment tool was used to
assess the risk of bias and the quality of the included literature. RevMan 5.4 software was used for
meta-analysis, and GRADE software was used to evaluate the quality of evidence for the outcome indicators.
Results: Ten studies involving 622 participants were included. The meta-analysis results showed that
acupuncture combined with rTMS significantly improved clinical efficacy in patients with post-stroke
depression [RR=1.14, 95% CI (1.06, 1.24), P=0.0009]. Moreover, the Hamilton Depression Scale (HAMD)
score [MD=－ 3.75, 95% CI (－ 5.86, － 1.64), P=0.0005] and Pittsburgh Sleep Quality Index (PSQI) score
showed significant improvement compared to the control group. The quality of evidence was rated as moderate
for clinical efficacy, low for HAMD score, and very low for PSQI score. Conclusion: Acupuncture combined
with rTMS demonstrates significant benefits in improving depression in patients after stroke. |
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