| An ideal animal model of post-stroke dysphagia can contribute to the in-depth understanding of its physiological and pathological pathogenesis, thus advancing the development of research on this disease. Due to the diversity of different types of models, researchers can choose appropriate animal models according to their research content and practical needs. In this paper, we reviewed the commonly used animal models of stroke dysphagia, including the selection of experimental animals, theoretical basis, modeling methods and model characteristics, etc. After comparing the photochemical method, which has the characteristics of high survival rate, precise injury at a fixed point, and certain advantages in assessing brain plasticity at the cellular and molecular levels, we briefly described the precautions for the application of the photochemical method to the local preparation of the post-stroke dysphagia model of mouse, aiming to provide a better solution for the study of post-stroke dysphagia in the brain. The precautions of applying photochemical method to prepare post-stroke dysphagia model in mice are briefly described, aiming to provide a reference for the basic research of post-stroke dysphagia. |