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| 中性粒细胞介导的炎症反应在急性缺血性脑卒中的研究进展 |
| Neutrophils mediated the research progress of the inflammatory response in acute ischemic stroke |
| 投稿时间：2024-05-30 修订日期：2024-05-30 |
| DOI： |
| 中文关键词: 急性缺血性脑卒中 中性粒细胞 炎症反应 神经保护 治疗策略 |
| 英文关键词: Acute ischemic stroke Neutrophils The inflammatory response Neuroprotection Treatment strategies |
| 基金项目: |
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| 中文摘要: |
| 急性缺血性脑卒中（Acute ischemic stroke，AIS）是一种常见且可能导致严重残疾的神经系统疾病。在AIS的发展过程中，中性粒细胞扮演着多面角色，既促进炎症反应，也参与神经组织的修复。本综述综合分析了中性粒细胞的特性、在AIS中的作用、炎症反应的多重影响，以及现有与新兴治疗策略。本文旨在通过全面审视文献，为深入理解AIS的病理机制、探索潜在治疗靶点，以及改善患者的长期预后提供科学依据。 |
| 英文摘要: |
| Acute ischemic stroke (AIS) is a common neurological disease that may lead to severe disability. Neutrophils play multifaceted roles in the development of AIS, both promoting inflammatory responses and participating in the repair of neural tissue. This review analyzed the characteristics of neutrophils, the role of the AIS, the multiple influences inflammation, as well as the existing and emerging treatment strategies. This review aims to provide a scientific basis for further understanding the pathological mechanism of AIS, exploring potential therapeutic targets, and improving the long-term prognosis of patients by comprehensively reviewing the literature. |
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