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| 持续性姿势知觉性头晕的亚型及其临床特征 |
| Subtypes and clinical features of persistent postural-perceptual dizziness |
| 投稿时间：2024-05-29 修订日期：2024-05-29 |
| DOI： |
| 中文关键词: 持续性姿势知觉性头晕，亚型，因子分析，聚类分析 |
| 英文关键词: Persistent postural-perceptual dizziness, subtypes, factor analysis, cluster analysis |
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| 中文摘要: |
| 目的：探索持续性姿势知觉性头晕可能存在的亚型及其临床特征，为临床治疗提供依据。方法：选取2023年5月-2023年12月就诊于山西省人民医院眩晕门诊诊断为持续性姿势知觉性头晕的106例病人，接诊时采取问卷调查的形式完成新泻PPPD问卷（NPQ）、眩晕障碍量表（DHI）、医院焦虑抑郁量表（HADS）、特质焦虑量表（STAI-T），对量表内容进行因子分析，随后根据因子分析的结果进行聚类分析，同时对每组病人进行特征分析。结果：因子分析揭示了3个因子，主动运动因子（32.82%）、视觉刺激因子（14.80%）、直立姿势因子（10.97%）。聚类分析揭示了3个亚型，视觉刺激优势亚型（n=25）、姿势控制优势亚型（n=24）、主动运动优势亚型（n=57）。各个亚型在年龄、职业、家族头疼史上有着显著差异（P＜0.05）。视觉刺激优势亚型年龄小、有明显的家族头疼史，职业以银行/超市职员为主，姿势控制优势亚型职业以公务员/教师为主，主动运动优势亚型以工人/农民为主。其他临床数据没有显著性差异。结论：PPPD最常见的加重因素是主动运动因素。可以分为3个亚型。各个亚型在年龄、职业、家族头疼史上有着显著特点。 |
| 英文摘要: |
| Objective: To investigate the potential subtypes and clinical characteristics of persistent postural -perceptual dizziness (PPPD)，providing evidence for clinical treatment. Methods: A total of 106 patients diagnosed with PPPD were selected from the Vertigo Clinic of Shanxi People's Hospital between May 2023 and December 2023. The Niigata PPPD questionnaire (NPQ), dizziness handicap inventory (DHI), Hospital Anxiety and Depression Scale (HADS), and State-trait anxiety inventory(STAI-T) were administered as a questionnaire survey upon admission. Factor analysis was conducted on the scale items, followed by cluster analysis based on the factor analysis results to analyze the characteristics of each patient subgroup. Results: Factor analysis revealed three factors, named active motor factor (32.82%), visual stimulation factor (14.80%), and Upright position factor (10.97%). Cluster analysis identified three subtypes: visual stimulation-dominant subtype (n=25), posture control-dominant subtype (n=24), and active motor-dominant subtype(n=57). Significant differences in age, occupation, and family history of headache were observed among these subtypes(P < 0.05). The visual stimulation-advantaged subtype consisted mainly of young individuals with a notable family history of headache who worked primarily as bank/supermarket staff; the Posture control-dominant subtype comprised civil servants/teachers; while the active motor-advantaged subtype included workers/farmers. No significant differences were found in other clinical data. Conclusion: Active exercise is identified as the most common exacerbating factor for PPPD, which can be classified into three distinct subtypes exhibiting significant variations in terms of age, occupation, and family history of headache. |
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