| 杨金花
，伍国锋
，罗莉
，王丽琨
，梁显泉.血肿形态不规则对脑出血患者术后再出血的影响[J].神经损伤功能重建,2024,(5):256-261 |
| 血肿形态不规则对脑出血患者术后再出血的影响 |
| Effect of Irregular Hematoma Morphology on Postoperative Rebleeding in IntracerebralHemorrhage Patients |
| |
| DOI： |
| 中文关键词: 血肿形态不规则 开颅手术 脑出血 术后再出血 |
| 英文关键词: irregular morphology craniotomy intracerebral hemorrhage postoperative rebleeding |
| 基金项目:国家自然科学基金
（载脂蛋白 E 模拟
肽(6KApoEp)激活
LRP1 抑 制 CypA/
NF-κ B/MMP-9 通
路降低脑出血后病
灶周围血脑屏障通
透性，No. 8226024
4） |
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| 中文摘要: |
| 目的：探讨头颅CT血肿形态不规则对开颅手术治疗自发性脑出血患者术后再出血的影响。方法：连
续纳入2019年1月至2022年9月贵州医科大学附属金阳医院神经外科收治的幕上脑出血患者348例，根据
术后是否再出血分为术后再出血组32例和非再出血组316例；根据血肿形态是否规则，分为血肿形态规则
组138例和血肿形态不规则组210例。所有患者均接受开颅血肿清除术；搜集患者一般临床资料、影像资
料、术后并发症等进行相关因素单因素分析。将单因素分析中差异有统计学意义（P＜0.05）的因素进行二
元Logistic回归分析，分析血肿形态不规则对脑出血患者术后再出血的预测价值。结果：血肿形态不规则
组患者术后再出血发生率（12.86%）高于血肿形态规则组（3.62%），两者比较具有统计学差异（P＜0.05），二
元Logistic回归分析显示血肿形态不规则可预测脑出血患者开颅血肿清除术后再出血，其敏感性、特异性
分别为0.844、0.421。结论：血肿形态不规则是脑出血患者术后再出血的独立危险因素。 |
| 英文摘要: |
| To explore effect of irregular hematoma morphology by preoperative CT on
postoperative rebleeding in patients with spontaneous intracerebral hemorrhage after craniotomy. Methods: A
total of 348 patients with intracerebral hemorrhage admitted to the neurosurgery department of Jinyang Hospital
affiliated to Guizhou Medical University from January 2019 to September 2022 were consecutively enrolled.
Based on postoperative rebleeding, they were divided into a postoperative rebleeding group (n=32) and a control
group (n=316). According to the hematoma morphology, patients were divided into a regular hematoma
morphology group (n=138) and an irregular hematoma morphology group (n=210). All patients underwent
craniotomy. General clinical data, imaging data and postoperative complications were collected, and univariate
analysis of related factors was performed. Factors with statistical significance (P<0.05) in the univariate analysis
were further analyzed using binary logistic regression analysis to assess the predictive value of irregular
hematoma morphology on postoperative rebleeding in patients with spontaneous intracerebral hemorrhage after
craniotomy. Results: The incidence of postoperative rebleeding was higher in the irregular hematoma
morphology group compared to the regular hematoma morphology group (12.86% v.s 3.62%), and there was a
statistical difference between the two groups (P<0.05). Binary Logistic regression analysis revealed that
irregular morphology could predict rebleeding in patients with intracerebral hemorrhage after craniotomy, with a
sensitivity and specificity of 0.844 and 0.421, respectively. Conclusion: Irregular hematoma morphology was
an independent risk factor for postoperative rebleeding in patients with intracerebral hemorrhage after
craniotomy. |
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