文章摘要
陈晓曼,张硕.卒中模拟病的研究现状及新进展:热点问题及预测方案[J].神经损伤功能重建,2023,(12):774-778
卒中模拟病的研究现状及新进展:热点问题及预测方案
Research Status and New Progress of Stroke Mimics: Hot Issues and Prediction Scheme
  
DOI:
中文关键词: 卒中模拟病  缺血性卒中  静脉溶栓  预测模型  量表
英文关键词: stroke mimics  ischemic stroke  intravenous thrombolysis  predictive modeling  scales
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作者单位
陈晓曼,张硕 中国医科大学 附属盛京医院 神经内科 
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中文摘要:
      急性缺血性卒中属于神经科急症,尽早治疗能够改善症状和减轻缺血性脑损伤。一部分患者的症状表 现为卒中样发病,与真性卒中临床特点相似,但实际为卒中模拟病(stroke mimics,SM)。SM包含一系列病因 及疾病状况。尽管可以通过影像学检查和临床症状对SM进行评估及快速识别,但仍有相当一部分患者可能 接受了不恰当的治疗,由此带来了潜在的药物治疗风险,同时挤占急诊医疗资源。因此,早期准确地鉴别SM 对于避免潜在药物治疗风险及延误原发性疾病的治疗至关重要。多模态影像学方案和基于临床特征的预测量 表有助于神经科医生在急诊环境下识别SM。本文总结了SM的患病率、疾病谱分布、临床特点、溶栓治疗的安 全性以及SM的鉴别诊断和预测工具。
英文摘要:
      Acute ischemic stroke (AIS) is a neurological emergency, and early treatment may improve symptoms and relieve ischemic brain injury. Some patients present with stroke-like symptoms, however the actual medical conditions are considered as“stroke mimics”. With similar clinical characteristics to true strokes, SM has been proved to include a series of etiologies and conditions. Although SM could be evaluated and rapidly recognized by imaging and clinical symptoms, some patients may receive inappropriate acute treatments, which brings certain drug treatment risks and emergency department crowding. Therefore, early and correctly identification of SM is essential for AIS to avoid potential risks of using AIS drugs and the delay in primary treatment. Multimodal imaging protocols and prediction scales based on clinical features can help neurologists identify SM in emergency situations. This review summarizes the prevalence of SM, the distribution of disorders spectrum, clinical features, safety of thrombolytic therapy, and differential diagnosis and prediction tools for SM.
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