卢飞臣,
,游雪梅
,李繁荣
,韦双双
,杨莉洁
,庞春华
,林景
,赵凤娟.原发性肝癌患者抑郁症状发生率的Meta分析[J].神经损伤功能重建,2023,(11):634-639 |
原发性肝癌患者抑郁症状发生率的Meta分析 |
Prevalence of Depressive Symptoms in Patients with Primary Liver Cancer: a Meta-analysis |
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DOI: |
中文关键词: 肝脏肿瘤 抑郁 发生率 Meta分析 |
英文关键词: liver neoplasms depressive symptom prevalence Meta-analysis |
基金项目:国家自然科学基金
项目(抑郁对肝癌
微环境免疫抑制状
态的正反馈作用机
制,No. 81960308);
广西科技厅重点研
发计划项目(基于
心理资本理论的肿
瘤医院护士工作倦
怠预测模型构建及
干 预 研 究 ,桂 科
AB18126042) |
|
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中文摘要: |
目的:系统评价国内外原发性肝癌(primary liver cancer,PLC)患者抑郁症状的发生率。方法:计算
机检索PubMed、Embase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、万
方数据库和维普数据库,收集关于国内外PLC患者抑郁症状发生率的文献,检索时限为建库至2022年4
月。2名研究者独立筛选文献、提取资料并评价纳入文献的偏倚风险后,采用Stata 16.0软件进行Meta分
析。结果:共纳入20篇文献。Meta分析结果显示,国内外PLC患者抑郁症状的发生率为47.1%(95%CI
38.7%~55.5%)。亚组分析结果显示,研究地域为国内、年龄<60岁、收入水平低、无工作、肿瘤分期为Ⅳ
期、治疗前、筛查工具为HADS的患者抑郁症状发生率更高。结论:PLC患者抑郁症状的发生率较高。 |
英文摘要: |
To systematically review the prevalence of depressive symptoms in patients with
primary liver cancer (PLC) worldwide. Methods: PubMed, Embase, The Cochrane Library, Web of Science,
China Biomedical Literature Database, CNKI, Wanfang database and VIP database were systematically
searched to identify literature investigating the prevalence of depressive symptoms in PLC patients from the
inception of these databases until April 2022. Two researchers independently screened the literature, extracted
data, and evaluated the risk of bias in the included literature. Meta-analysis was performed using Stata 16.0
software. Results: A total of 20 literatures were included. Meta-analysis results showed that the prevalence of
depressive symptoms in PLC patients was 47.1% (95%CI 38.7%~55.5% ). The results of subgroup analysis
showed that higher rates of depression were observed in patients with the following characteristics: Chinese, <
60 years old, low income, unemployment, stage Ⅳ tumor, no treatment and assessment using the HADS
screening tool. Conclusion: PLC patients had a high prevalence of depressive symptoms. |
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