| 张洋铭
，魏怡名
，唐振刚.难治性癫痫的外科诊疗进展[J].神经损伤功能重建,2023,(6):346-348 |
| 难治性癫痫的外科诊疗进展 |
| Progress in Surgical Diagnosis and Treatment of Drug-resistant Epilepsy |
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| DOI： |
| 中文关键词: 癫痫 外科治疗 术前评估 定位 |
| 英文关键词: epilepsy surgical treatment preoperative assessment location |
| 基金项目: |
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| 中文摘要: |
| 癫痫是由各种原因引起的脑神经元高度同步化异常放电所致的临床综合征，其患病率为 0.8%～
1.2%。30%～40%的癫痫患者呈药物难治性（规律使用一线抗癫痫药物2年仍不能充分控制癫痫发作），其
中10%～50%该类患者可以选择癫痫手术治疗。癫痫手术旨在通过切除致痫灶控制癫痫发作，同时通过保
留重要的大脑功能区域以避免神经心理和功能出现障碍。本文就难治性癫痫外科手术过程中的术前评估、
致痫灶定位、手术方式的选择及手术预后等几个方面综述如下。 |
| 英文摘要: |
| Epilepsy is a clinical syndrome caused by highly synchronous abnormal discharge of neurons in the
brain, which is caused by a variety of reasons. With a prevalence of 0.8% to 1.2%, epilepsy represents one of the
most frequent chronic neurological disorders. 30% to 40% of patients suffer from drug-resistant epilepsy (regular use of first-line antiepileptic drugs for 2 years still cannot adequately control seizures). Epilepsy surgery represents a valuable treatment option for 10% to 50% of these patients. Epilepsy surgery aims to control seizures
by resection of the epileptogenic tissue while avoiding neuropsychological and functional disorders by sparing
essential brain areas. In this paper, the preoperative evaluation, location of epileptogenic focus, choice of operative mode and prognosis of refractory epilepsy surgery are summarized. |
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