文章摘要
董露露 ,王璐璐 ,王天俊.5-羟色胺递质系统与帕金森病非运动症状的关系研究进展[J].神经损伤功能重建,2023,(3):158-160
5-羟色胺递质系统与帕金森病非运动症状的关系研究进展
Research Progress of Relationship between the 5-HT Transmitter System and theNon-motor Symptoms of Parkinson's Disease
  
DOI:
中文关键词: 帕金森病  5-羟色胺  非运动症状
英文关键词: Parkinson's disease  5-HT  non-motor symptoms
基金项目:国家自然科学基金 (No. 81241037)
作者单位
董露露1 ,王璐璐2 ,王天俊3 1. 河北北方学院研究 生院 2. 华北理工大学研究 生院 3. 河北省人民医院神 经内二科 
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中文摘要:
      目前较多研究已揭示帕金森病(PD)运动症状的病理生理机制及治疗,然而针对其非运动症状 (NMS)的形成机制及用药较有限,并且多数患者在确诊前早已出现未受关注的NMS。近年来,国内外研 究发现5-羟色胺(5-HT)与PD-NMS及治疗用药之间存在密切联系。本文就目前常见的NMS与5-HT之 间的关系及治疗用药进行综述。
英文摘要:
      More studies have revealed the pathophysiological mechanisms and treatment of motor symptoms in Parkinson's disease (PD), but the mechanisms and medications for non-motor symptoms (NMS) are more limited, and most patients develop unattended NMS long before diagnosis. In recent years, domestic and international studies have identified a strong link between 5-hydroxytryptamine (5-HT) and PD-NMS and the medication used to treat it. In this paper, we review the current relationship between NMS and 5-HT and its therapeutic use.
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