| 陈雪梅，余广兰.血流限制联合低强度抗阻运动在脑梗死合并肌少症老年患者的应用研究[J].神经损伤功能重建,2023,(1):23-27 |
| 血流限制联合低强度抗阻运动在脑梗死合并肌少症老年患者的应用研究 |
| Application of Blood Flow Restriction Combined with Low-Intensity Resistance Exercise inElderly Patients with Cerebral Infarction and Sarcopenia |
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| DOI： |
| 中文关键词: 肌少症 脑梗死 血流限制 抗阻训练 老年 |
| 英文关键词: sarcopenia cerebral infarction blood flow restriction resistance exercise elderly |
| 基金项目: |
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| 摘要点击次数: 1198 |
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| 中文摘要: |
| 目的：观察血流限制（BFRT）联合低强度抗阻训练对脑梗死合并肌少症老年患者肌肉力量、体能及日
常生活能力的影响。方法：脑梗死合并肌少症老年患者71例，随机分为观察组35例及对照组36例。2组予
以低强度抗阻训练，观察组加BFRT。训练前及12周后，采用握力评估肌肉力量，简易机体功能评估法（SPPB）评价体能，改良Barthel指数（MBI）评估日常生活能力，并检测肌少症相关生物标志物：生长激素（GH）、
胰岛素样生长因子1（IGF-1）及白细胞介素-6（IL-6）。结果：训练后，观察组的握力、SPPB评分及MBI评分
高于对照组（P＜0.01），ASM、SMI 评分及 ASMI 高于对照组（P＜0.05 或 P＜0.01），GH、IGF-1 高于对照组
（P＜0.01），观察组IL-6低于对照组（P＜0.01）。结论：BFRT联合低强度抗阻训练能改善脑梗死合并肌少症
老年患者的肌肉力量、体能及日常生活能力，提高其骨骼肌质量，促进合成代谢激素分泌并降低炎症因子水
平。 |
| 英文摘要: |
| To observe the effect of blood flow restriction (BFRT) combined with low-intensity
resistance training on muscle strength, physical fitness and activities of daily living in elderly patients with
cerebral infarction complicated with sarcopenia. Methods: Seventy-one elderly patients with cerebral infarction
complicated with sarcopenia were randomly divided into the observation group (35 cases) and control group (36
cases). The 2 groups were given low-intensity resistance training, and the observation group was given BFRT.
Before training and 12 weeks after training, muscle strength was evaluated by grip strength, physical fitness was
evaluated by the short physical performance battery (SPPB), and activities of daily living were evaluated by the
modified Barthel Index (MBI); additionally, myopenia-related biomarkers including growth hormone (GH),
insulin-like growth factor-1 (IGF-1), and interleukin-6 (IL-6) were detected. Results: After training, the grip
strength, SPPB score, and MBI score of the observation group were higher than those of the control group (P<
0.01). The ASM, SMI and ASMI scores in the observation group were higher than those in the control group (P<
0.05 or P<0.01). The levels of GH and IGF-1 in the observation group were higher than those in the control
group (P<0.01). The level of IL-6 in the observation group was lower than that in the control group (P<0.01).
Conclusion: BFRT combined with low-intensity resistance training can improve the muscle strength, physical
fitness, and activities of daily living of elderly patients with cerebral infarction and sarcopenia, improve the
quality of skeletal muscle, promote the secretion of anabolic hormones, and reduce the level of inflammatory
factors. |
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