| 彭涛，张紫霓，朱碧峰，刘建林，彭小祥.急性基底动脉闭塞患者血管内治疗不良预后的预测因素[J].神经损伤功能重建,2022,17(12):753-756 |
| 急性基底动脉闭塞患者血管内治疗不良预后的预测因素 |
| Predictors of Poor Prognosis after Endovascular Treatment in Patients with Acute Basilar Ar⁃tery Occlusion |
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| DOI： |
| 中文关键词: 基底动脉闭塞 血管内治疗 影响因素 预后 |
| 英文关键词: basilar artery occlusion endovascular treatment influencing factors prognosis |
| 基金项目:湖北省卫生健康委
科研项目（No.WJ2
021F129） |
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| 中文摘要: |
| 目的：探索发病24 h内急性基底动脉闭塞患者血管内治疗术后不良预后的预测因素。方法：回顾性
纳入2016年1月1日至2020年10月31日在湖北省第三人民医院神经内科进行了血管内治疗的急性基底动
脉闭塞患者42例，收集患者的人口统计学及临床资料。根据术后90 d的mRS评分，将患者分为预后良好组
和预后不良组。统计分析2组患者的临床数据，应用多因素Logistic回归分析确定急性基底动脉闭塞血管
内治疗患者预后的独立影响因素，应用ROC曲线探索最佳界值。结果：单因素分析显示2组的基线美国国
立卫生院脑卒中量表（NIHSS）评分、格拉斯哥昏迷量表（GCS）评分、BATMAN评分差异具有统计学意义。
多因素Logistic回归分析显示，高NIHSS评分和低BATMAN评分为急性基底动脉闭塞患者血管内治疗术后
不良预后的独立影响因素。ROC曲线分析显示，BATMAN评分预测不良预后的准确性较高，其ROC曲线
下面积为0.871，最佳界值为6.5，特异度为81.3%，灵敏度为80.8%。结论：高基线NIHSS评分和低BATMAN
评分为急性基底动脉闭塞患者血管内治疗术后不良预后的独立影响因素；当BATMAN评分＜6.5时，其预
测不良预后的特异度为81.3%，灵敏度为80.8%。 |
| 英文摘要: |
| To explore the predictors of poor prognosis after endovascular treatment in patients with
acute basilar artery occlusion within 24 hours of onset. Methods: We collected the demographic and clinical data of patients with acute basilar artery occlusion who underwent endovascular treatment in the Department of
Neurology, Hubei Third People’s Hospital from January 1, 2016 to October 31, 2020. According to the mRS
score 90 days after surgery, patients were divided into the good prognosis group and poor prognosis group. The
clinical data of the two groups were statistically analyzed. Multivariate Logistic regression analysis was used to
determine the independent prognostic factors of patients with acute basilar artery occlusion endovascular treatment. The ROC curve was applied to determine the best boundary value. Results: Univariate analysis showed
that the differences in baseline NIHSS score, GCS score, and MRA-BATMAN score were statistically significant
between the two groups. Multivariate Logistic regression analysis showed that high NIHSS score and low
MRA-BATMAN score were independent factors influencing poor prognosis after endovascular treatment of
acute basilar artery occlusion. ROC curve analysis showed that MRA-BATMAN score was accurate in predicting
poor prognosis. The area under the ROC curve of MRA-BATMAN score predicting poor prognosis was 0.871.
The best cut-off value of MRA-BATMAN score was 6.5, its specificity for predicting poor prognosis was 81.3%,
and its sensitivity was 80.8%. Conclusion: High baseline NIHSS score and low DWI-BATMAN score were independent factors affecting poor prognosis in patients after endovascular treatment of acute basilar artery occlusion. When the MRA-BATMAN score was less than 6.5, the specificity of predicting poor prognosis was 81.3%,
and the sensitivity was 80.8%. |
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