文章摘要
胡胜旗,徐伟东,厉华,陈如东.镜像后交通动脉瘤破裂的形态学危险因素分析[J].神经损伤功能重建,2022,17(10):575-578
镜像后交通动脉瘤破裂的形态学危险因素分析
Morphological Evaluation of Risk of Mirror Posterior Communicating Artery Aneurysm Rup⁃ture
  
DOI:
中文关键词: 后交通动脉动脉瘤  镜像动脉瘤  破裂  形态学参数  危险因素
英文关键词: posterior communicating artery aneurysm  mirror aneurysm  rupture  morphological parameter  risk factor
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作者单位
胡胜旗,徐伟东,厉华,陈如东 华中科技大学同济 医学院附属同济医 院神经外科 
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中文摘要:
      目的:分析镜像后交通动脉瘤的形态学指标以评估动脉瘤破裂风险。方法:回顾性分析39对破裂的 镜像后交通动脉瘤的形态学参数,将以下参数纳入条件Logistic回归:动脉瘤高度、宽度、颈宽、尺寸比、纵横 比、宽/颈比、高/宽比、颈内动脉直径、是否有子瘤及动脉瘤高度>宽度。将单因素分析中与破裂有显著相关 (P<0.05)的参数纳入多因素回归分析。在本中心的 434 例后交通动脉瘤患者中使用受试者特征曲线 (ROC)和曲线下面积(AUC)检验独立危险因素的预测敏感性和特异性。结果:动脉瘤有子瘤(OR=8.852, P=0.024)、动脉瘤高度>宽度(OR=18.250,P=0.011)和动脉瘤宽度(OR=1.645,P=0.024)是后交通动脉瘤破裂 的独立危险因素,其AUC值分别为0.737、0.761及0.686。结论:动脉瘤宽度、动脉瘤高度>宽度和有子瘤可 能是后交通动脉瘤破裂的形态学独立危险因素;其中子瘤形成是评估后交通动脉瘤破裂风险的最佳因素。
英文摘要:
      To assess the risk of rupture using morphological parameters of mirror posterior communicating artery (PcoA) aneurysms. Methods: We retrospectively analyzed the morphological parameters of 39 pairs of ruptured mirror PcoA aneurysms. We performed conditional univariate and multivariate logistic regression for the following morphological parameters: aneurysm height, width, neck width, size ratio, aspect ratio, bottle/neck factor, height/width ratio, internal carotid artery diameter, daughter sac presence and whether height > width. Multivariate regression analysis was performed on the factors found by univariate analysis to have significant correlation with aneurysm rupture (P<0.05). We used receiver operating characteristics (ROC) and the area under the curve (AUC) to test the predictive accuracy of the independent factors for 434 PcoA aneurysm cases in our database. Results: Presence of a daughter sac (OR=8.852, P=0.024), aneurysm with height > width (OR= 18.250, P=0.011), and aneurysm width (OR=1.645, P=0.024), were independent risk factors for the rupture of PcoA aneurysms. The AUC of these factors were 0.737, 0.761, and 0.686, respectively. Conclusion: Aneurysm width, aneurysm with height > width, and daughter sac presence may be independent risk factors for the rupture of PcoA aneurysms. Among these, daughter sac presence was the most accurate predictor for rupture.
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