文章摘要
李锋森 ，孟毅 ，乔明亮 ，成家宏.前庭康复训练联合药物疗法治疗持续性姿势-知觉性头晕的Meta分析[J].神经损伤功能重建,2022,17(5):264-268
前庭康复训练联合药物疗法治疗持续性姿势-知觉性头晕的Meta分析
Meta-Analysis of Vestibular Rehabilitation Training Combined with Drug Therapy inTreatment of Persistent Postural-Perceptual Dizziness
  
DOI：
中文关键词: 持续性姿势-知觉性头晕  慢性主观性头晕  前庭康复训练  Meta 分析
英文关键词: persistent posture-perceptual dizziness  chronic subjective dizziness  vestibular rehabilitation training  meta-analysis
基金项目:
作者单位
李锋森1 ，孟毅2 ，乔明亮2 ，成家宏1 1. 河南中医药大学 2. 河南省中医院 
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中文摘要:
      目的：通过Meta分析评价前庭康复训练联合药物疗法治疗持续性姿势-知觉性头晕（PPPD）的疗效。 方法：制定检索策略，检索 Cochrane Library、Pubmed、Web of Science、维普数据库（VIP）、中国期刊全文数据 库（CNKI）、万方数据库（Wangfang）建库到2021年3月关于前庭康复训练联合药物治疗PPPD的临床随机对 照试验，由 2 名研究人员严格按照纳入排除标准独立筛选文献、提取数据、评价文献质量，运用 Review Manager 5.3软件进行质量评价及Meta分析。结果：筛选后最终得到10篇文献，均为随机对照实验，共计 904例PPPD患者。Meta分析结果显示，与常规药物治疗相比，前庭康复训练联合药物治疗能有效缓解头晕 症状[MD=－7.19，95%CI（－9.52，－4.86），P＜0.01]，缓解焦虑情绪[MD=－2.45，95%CI（－4.39，－0.51）， P＜0.01]及抑郁情绪[MD=－3.59，95%CI（－6.10，－1.09），P＜0.01]，提高有效率[OR=2.46，95%CI（1.43， 4.21），P＜0.01]。结论：前庭康复训练联合药物治疗PPPD与常规药物治疗相比，能有效改善患者主观头晕 症状，并且缓解焦虑抑郁情绪。
英文摘要:
      To evaluate efficacy of vestibular rehabilitation training combined with drug therapy in the treatment of persistent postural-perceptual dizziness (PPPD) by meta-analysis. Methods: A search strategy was established to search the Cochrane Library, Pubmed, Web of Science, VIP database (VIP), China Journal full-text database (CNKI), and Wanfang database (Wanfang) for clinical randomized controlled trials of vestibular rehabilitation training combined with drugs in the treatment of PPPD from up to March 2021. Two researchers independently screened the literature, extracted data, and evaluated the quality of the literature. Meta-analysis was carried out using Review Manager 5.3 software. Results: After final screening, 10 articles were obtained, all of which were randomized controlled trials, with a total of 904 patients with PPPD. Results of the meta-analysis showed that, compared with conventional drug therapy, vestibular rehabilitation training combined with drug therapy relieved symptoms of dizziness [MD=－7.19, 95%CI (－9.52, －4.86), P<0.01], anxiety [MD=－2.45, 95%CI (－4.39, －0.51), P<0.01], and depression [MD=－3.59, 95%CI (－6.10, －1.09), P<0.01] and increased the effective rate [OR=2.46, 95% CI (1.43, 4.21), P<0.01]. Conclusion: Vestibular rehabilitation training combined with drugs is effective in the treatment of PPPD. Compared with conventional drug therapy, vestibular rehabilitation training combined with drugs can better improve the subjective symptoms of dizziness and reduce the negative emotions of anxiety and depression.
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