| 刘凤霞，连亚军，刘洪波，孟祥荷，杜丽媛，李钰娟，谢南昌.吉兰-巴雷综合征发生排尿障碍的危险因素及儿童患者排尿障碍发生率的Meta分析[J].神经损伤功能重建,2022,17(2):72-75 |
| 吉兰-巴雷综合征发生排尿障碍的危险因素及儿童患者排尿障碍发生率的Meta分析 |
| A Meta-Analysis of Risk Factors for Urination Disorders in Patients with Guillain-Barre Syn⁃drome and Incidence of Urination Disorders in Child Patients |
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| DOI： |
| 中文关键词: 吉兰-巴雷综合征 排尿障碍 危险因素 发生率 Meta分析 |
| 英文关键词: Guillain-Barre syndrome urination disorders risk factors incidence rate meta-analysis |
| 基金项目:国家自然科学基金
（No. 81971214）；
河南省医学科技攻
关计划省部共建青
年项目（No. SB201
902011）；
郑州大学青年骨干
教师培养计划培养
人选项目（No. 201
9ZDGGJS056） |
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| 中文摘要: |
| 目的：探讨吉兰-巴雷综合症（GBS）患者发生排尿障碍的危险因素及儿童患者排尿障碍的发生率。 方法：在Pubmed和中国知网数据库中检索GBS排尿障碍的文献，检索时间截止2019年12月23号。使用美
国卫生保健质量和研究机构（AHRQ）制定的横断面研究质量评价标准进行质量评价。采用R3.6.3软件进
行Meta分析，合并效应量为比值比（OR）和95%置信区间（CI）。结果：共纳入15项研究，有6项研究存在拟
研究的有关危险因素的结局指标，结果显示：肌电图类型（OR=1.07, 95%CI =0.61-1.89, P=0.81）、脑神经受累
（OR=1.73, 95%CI =0.38-7.85, P=0.48）在排尿障碍组与无排尿障碍组差异无统计学意义；Hughes评分（OR= 0.23, 95%CI= 0.11-0.50, P=0.00）在排尿障碍组与无排尿障碍组之间差异有统计学意义。有9项研究被纳入
儿童患者排尿障碍发生率的 Meta 分析中，结果显示：儿童患者排尿障碍发生率为 10.5%（95% CI= 0.05-0.16）。结论：高Hughes 评分是GBS患者排尿障碍的危险因素；儿童患者排尿障碍的发生率为10.5%。 |
| 英文摘要: |
| To investigate the risk factors for urination disorders in patients with Guillain-Barre syndrome (GBS) and the incidence of urination disorders in child patients. Methods: We systematically retrieved
literature published in PubMed and CNKI up to December 23, 2019 related to urination disorders in GBS patients. The quality of the study was assessed by Agency for Healthcare Research and Quality (AHRQ) guidelines
for cross-sectional studies. Meta-analysis was performed by R3.6.3 software, and the combined effect size included the odds ratio (OR) and 95% confidence interval (CI). Results: A total of 15 studies were included. There
were 6 studies with our desired outcome indicator. The results showed there was no significant difference in
EMG type (OR=1.07, 95%CI=0.61-1.89, P=0.81) and cerebral nerve involvement (OR=1.73, 95%CI= 0.38-7.85, P=0.48) between patients with urination disorders and without. However, there was a statistically significant difference in Hughes score (OR=0.23, 95%CI=0.11-0.50, P=0.00) between the two groups. Nine studies were included in the meta-analysis of incidence of urination disorders in child patients, and the results showed a 10.5%
incidence (95% CI=0.05-0.16). Conclusion: A high Hughes score was a risk factor for urination disorders in patients with GBS, and the incidence of urination disorders in child patients was 10.5%. |
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