| 刘基
，王蒙恩
，惠鑫
，张利军
，张童童
，陈旺
，王贤军.急性前循环缺血性卒中血管内治疗再通后不良预后的影响因素分析[J].神经损伤功能重建,2022,17(1):13-16 |
| 急性前循环缺血性卒中血管内治疗再通后不良预后的影响因素分析 |
| Analysis of Factors Influencing Poor Outcomes of Acute Ischemic Stroke after EndovascularTreatment and Recanalization |
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| DOI： |
| 中文关键词: 急性缺血性卒中 血管内治疗 预后 预测因素 |
| 英文关键词: acute ischemic stroke endovascular therapy prognosis predictors |
| 基金项目:山东省医药科技卫
生 发 展 计 划 项 目
（No. 2019WS128） |
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| 中文摘要: |
| 目的：探讨血管内治疗（EVT）急性前循环大动脉闭塞性卒中（AC-LAO）患者血管再通后不良预后的
影响因素。方法：回顾性分析行EVT且血管成功再通的145例AC-LAO患者临床资料，依据术后90 d改良
Rankin量表（mRS）评分分为预后良好组（mRS≤2分）和预后不良组（mRS＞3分）。单因素分析2组患者的
基线资料、神经功能损伤状况、危险因素、Rapid软件和血管造影成像参数等资料，多因素Logistic 回归探讨
影响血管内再通治疗后预后不良的独立影响因素。结果：145 例实现血管再通的患者中，65例患者术后
90 d mRS 评分＞3 分，预后不良率为 44.83%。多因素 Logistic 回归显示入院时高 NIHSS 评分（OR 0.866，
95%CI 0.794～0.943，P=0.001）、低 Aspect 评分（OR 1.607，95%CI 1.181～2.186，P=0.003）、不良侧支循环
（OR 0.373，95%CI 0.163～0.856，P=0.020）是影响预后的独立危险因素。结论：入院NIHSS评分、Aspect评 分、侧支循环状态是影响AC-LAO患者早期血管再通后不良预后的独立危险因素。 |
| 英文摘要: |
| To explore influencing factors of poor outcomes of anterior circulation large artery
occlusion (AC-LAO) after endovascular therapy (EVT). Methods: Retrospective analysis was made on the
clinical data of 145 patients with AC-LAO who were successfully recanalized after endovascular treatment.
According to the modified Rankin scale (mRS) scores 90 d after surgery, patients were divided into the good
prognosis group (mRS score ≤ 2）and poor prognosis group (mRS score＞3). Univariate analysis was performed
on baseline data, neurological status, risk factors, Rapid software evaluation, angiographic parameters, and other
data of patients in the two groups. Multivariate Logistic regression was used to explore the independent factors
influencing poor prognosis after recanalization following endovascular treatment. Results: Among the 145
patients with recanalization, 65 had an mRS score＞3 after surgery, and the poor prognosis rate was 44.83% .
Multivariate Logistic regression showed that a high NIHSS score (OR 0.866, 95%CI 0.794～0.943, P=0.001),
low Aspect score (OR 1.607, 95%CI 1.181～2.186, P=0.003), and poor lateral vascular circulation (OR 0.373,
95% CI 0.163～0.856, P=0.020) at the time of admission were independent risk factors for poor prognosis.
Conclusion: For AC-LAO patients, the NIHSS score, Aspect score, and collateral circulation status at the time
of admission are independent risk factors for poor prognosis early after recanalization. |
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