| 王磊，周晓琴.不同性别慢性精神分裂症患者认知功能障碍的差异[J].神经损伤功能重建,2021,16(6):340-343 |
| 不同性别慢性精神分裂症患者认知功能障碍的差异 |
| Differences in Cognitive Dysfunction of Schizophrenic Patients with Different Genders |
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| DOI： |
| 中文关键词: 精神分裂症 性别 认知功能障碍 |
| 英文关键词: schizophrenia gender cognitive dysfunction |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨不同性别慢性精神分裂症患者认知功能障碍的差异及其影响因素。方法：我院收治的慢
性精神分裂症住院患者135例纳入研究，根据性别分为男性组71例，女性组64例。采用阳性和阴性症状量
表（PANSS）评定患者的临床症状，蒙特利尔认知评估量表（MoCA）评估患者的认知功能，对结果进行统计
学分析。结果：男性组PANSS的阴性症状分高于女性组，男性组在MoCA总分、视空间与执行功能、记忆力
项目上评分低于女性组，差异均有统计学意义（P＜0.05）；经协方差分析后，男性记忆力评分仍低于女性患
者（P＜0.01）。结论：慢性精神分裂症男性患者认知功能障碍较女性严重，记忆障碍尤为明显。 |
| 英文摘要: |
| To explore the differences in cognitive dysfunction of schizophrenic patients with different genders and analyze the influencing factors. Methods: 135 patients with chronic schizophrenia treated in
our hospital were enrolled in this study and were divided into the male group (n=71) and female group (n=64).
Clinical symptoms were assessed by the positive and negative symptom scale (PANSS), and cognitive functions
were assessed by the Montreal cognitive assessment (MoCA). The results were statistically analyzed. Results:
The negative symptom score in PANSS of male patients was higher than that of female patients, but male patients had significantly lower scores in total score, visual space and executive function score, and memory score
in MoCA than those of female patients (P<0.05). After covariance analysis, the memory score of male patients
was still lower than that of female patients (P<0.01). Conclusion: Male patients with chronic schizophrenia suffer more serious cognitive dysfunction than female patients, especially in memory impairment. |
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