| 郁满华
，李军文
，叶子翔
，童禹浩
，刘晓英.重复经颅磁刺激治疗脑卒中后吞咽障碍疗效的Meta分析[J].神经损伤功能重建,2021,16(6):311-315 |
| 重复经颅磁刺激治疗脑卒中后吞咽障碍疗效的Meta分析 |
| Efficacy of Repetitive Transcranial Magnetic Stimulation on Post-Stroke Dysphagia: A Me⁃ta-analysis Y |
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| DOI： |
| 中文关键词: 吞咽障碍 重复经颅磁刺激 脑卒中 Meta分析 |
| 英文关键词: dysphagia repetitive transcranial magnetic stimulation stroke Meta- analysis |
| 基金项目:2020 年 成 都 市 医
学 科 研 课 题（No.
2020065） |
|
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| 中文摘要: |
| 目的：系统评价不同频率的重复经颅磁刺激（rTMS）刺激不同部位对不同分期卒中后吞咽障碍（PSD）
的疗效，以及rTMS对改善患者吞咽相关生活质量的影响。方法：检索国内外数据库中采用rTMS治疗PSD
的随机对照试验，根据Cochrane手册5.1.0版评价纳入文献的质量，采用RevMan5.3进行数据分析。结果：
共纳入17篇，629例样本。Meta分析结果显示：在脑卒中恢复期，rTMS较常规吞咽治疗能够更明显改善
PSD患者的吞咽功能（P＜0.05）；高频双侧、高频健侧和低频健侧rTMS治疗均能有效地改善脑PSD患者的
吞咽功能（P＜0.05）；rTMS对改善PSD患者吞咽相关生活质量无明显作用（P＞0.05）。结论：脑卒中恢复期
的高频双侧、高频健侧和低频健侧的rTMS治疗PSD的疗效较好，但对吞咽相关功能障碍的生活质量改善
不明显。 |
| 英文摘要: |
| A Meta-analysis was conducted to investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on post-stroke dysphagia (PSD), with different frequencies and stimulation locations, and
on the improvement of swallowing-related quality of life. Methods: Multiple electronic databases were
searched for randomized controlled trials which met the included standards. Cochrane handbook 5.1.0 and RevMan 5.3 software were separately used for the quality evaluation and Meta-analysis. Results: A total of 17 articles with 629 patients were included. The results had shown that rTMS could more effectively improve PSD
than that of the conventional swallowing therapy in convalescent stage (P＜0.05), high-frequency rTMS on bilateral sides or unaffected side and low-frequency rTMS on unaffected side could effectively improve PSD (P＜ 0.05). And rTMS had no significant effect on improving the swallowing-related quality of life in the patients
with PSD (P＞0.05). Conclusion: In convalescent stage, high-frequency rTMS on bilateral sides or unaffected
side and low-frequency rTMS on unaffected side could effectively improve PSD, but there was no significant improvement in the swallowing-related quality of life in PSD patients. |
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