| 谢艺妙，倪朝民，吴鸣.脊髓损伤患者并发低蛋白血症的相关危险因素分析[J].神经损伤功能重建,2021,16(4):206-208 |
| 脊髓损伤患者并发低蛋白血症的相关危险因素分析 |
| Analysis of Risk Factors of Hypoproteinemia in Patients with Spinal Cord Injury |
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| DOI： |
| 中文关键词: 脊髓损伤 低蛋白血症 危险因素 |
| 英文关键词: spinal cord injury hypoproteinemia risk factors |
| 基金项目: |
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| 摘要点击次数: 3733 |
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| 中文摘要: |
| 目的：分析脊髓损伤（SCI）患者并发低蛋白血症（HA）的相关危险因素。方法：回顾性分析2019年6月 至2020年10月我院康复医学科收治的SCI患者112例，入院时完善血清总蛋白和白蛋白检查。根据检查结
果，将患者分为HA组和非HA组，记录2组患者的性别、年龄、病程、损伤节段（四肢瘫与截瘫）、损伤程度（完
全性脊髓损伤与非完全性脊髓损伤）、有无并发症（肺部感染和下肢深静脉血栓的形成）等临床资料，并在入
院第2日清晨完善血糖、肌酐、血清镁浓度、淋巴细胞数量等检查。先采用单因素分析，再根据分析结果进行
多因素Logistic回归分析，筛选出SCI患者并发HA的相关危险因素。结果：单因素分析显示，年龄、病程、四
肢瘫、完全性脊髓损伤、肺部感染、下肢深静脉血栓形成、血糖及淋巴细胞数量可能与SCI患者HA的发生
有关（P＜0.05）；Logistic 回归分析显示，肺部感染和下肢深静脉血栓形成是 SCI 患者并发HA的危险因素。
结论：肺部感染和下肢深静脉血栓形成可能是SCI患者并发HA的危险因素。 |
| 英文摘要: |
| To analyze the relevant risk factors of hypoalbuminemia (HA) in patients with spinal cord
injury (SCI). Methods: We performed a retrospective analysis of 112 patients with SCI admitted to the Department of Rehabilitation Medicine in our hospital from June 2019 to October 2020 and perfected serum total protein
and albumin examinations upon admission. According to examination results, the patients were divided into the
HA group and non-HA group, and the gender, age, course of disease, segment of injury (tetraplegia and paraplegia), degree of injury (complete spinal cord injury and incomplete spinal cord injury), and presence or absence of
complications (pulmonary infection and deep vein thrombosis of the lower extremities) were recorded. Collection
of clinical data such as blood glucose, creatinine, serum magnesium concentration, and lymphocyte count was
completed early morning on the day following admission. First, single-factor analysis was used, and multi-factor
logistic regression analysis was performed according to the analysis results to screen for relevant risk factors of
HA in patients with SCI. Results: Univariate analysis showed that age, course of disease, quadriplegia, complete
spinal cord injury, lung infection, deep vein thrombosis of the lower limbs, blood sugar, and lymphocyte count
may be related to the occurrence of HA in SCI patients (P<0.05). Regression analysis showed that lung infection
and deep vein thrombosis of the lower extremities were risk factors for the occurrence of HA in SCI patients. Con⁃
clusion: Pulmonary infection and deep vein thrombosis of lower limbs may be the risk factors of HA in patients
with SCI. |
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