| To analyze the clinical features, treatment, and prognosis of patients with herpes virus
infection after microvascular decompression. Methods：We reported the clinical data of 2 patients with herpes
virus infection after microvascular decompression and retrospectively analyzed the relevant literature. Results：
A literature search revealed 7 previous cases fulfilling the criteria of this study. We combined these 7 cases with
our 2 and analyzed a total of 9 cases. Among them, 5 were infected by the varicella-zoster virus, 3 by the herpes
simplex virus, and 1 by an unidentified virus; 6 cases had primary trigeminal neuralgia, and 3 had hemifacial
spasm. The most common symptom was facial herpes (5 cases). Some patients developed atypical symptoms
such as fever and headache (4 cases), ocular conjunctivitis (1 case), facial paralysis (1 case), and facial muscle
spasm (1 case). All the patients were given acyclovir for antiviral treatment; clinical symptoms were subsequently improved, and prognosis was good. Conclusion：The clinical features of fever, facial pain, facial muscle
spasm, facial paralysis, and ocular symptoms after microvascular decompression may indicate herpes virus infection. Physicians should closely monitor the patients’skin for the presence of herpes, perform serological or cerebrospinal fluid virus testing when necessary, and administer antiviral treatment in a timely manner. |