文章摘要
张娜, ，刘仲仲, ，蔺文娟 ，逯青丽, ，蔺雪梅, ，王芳, ，史亚玲, ，王清, ，刘国正, ，吴松笛,,.西安地区急性卒中患者体质量指数与早期预后的关系研究[J].神经损伤功能重建,2021,16(3):135-140
西安地区急性卒中患者体质量指数与早期预后的关系研究
Relationship between Body Mass Index and Early Prognosis in Patients with Acute Stroke inXi’an Region
  
DOI：
中文关键词: 急性卒中  体重指数  早期预后
英文关键词: acute stroke  body mass index  early prognosis
基金项目:陕西省科技计划 项目（No. 2017SF 163）；西 安 市 科 技计划重大项目 [No. 201805104Y X12SF38(2)]；西 安市科技计划项 目[No. 20YXYJ0 008（1）]；西安市 卫健委科研项目 （No. 2020ms03）； 西安市卫健委科 研项目（No. 2020 yb05）
作者单位
张娜1,2 ，刘仲仲1,2 ，蔺文娟3 ，逯青丽1,2 ，蔺雪梅1,2 ，王芳1,2 ，史亚玲1,2 ，王清1,2 ，刘国正1,2 ，吴松笛1,2,3 1. 西安市第一医 院神经内科 2. 西北大学附属 第一医院神经内 科 3. 西北大学生命 科学学院 
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中文摘要:
      目的：探讨西安地区急性卒中患者体质量指数（BMI）与早期预后的关系。方法：纳入西安市4所三级 甲等医院2015年1～12月连续入院的急性卒中患者的临床资料，比较分析不同BMI范围（按BMI分为体质 量过低组、体质量正常组、超重组及肥胖组）患者的临床特征，随访90 d的结局事件（包括卒中复发、死亡和 预后不良）。通过单因素和多因素 Logistic 回归分析，探讨西安地区急性卒中患者 BMI 与早期预后的关 系。结果：最终纳入急性卒中患者2 692例，平均年龄（63.58±12.46）岁。90 d随访发现，体质量过低组死亡 率明显较高（体质量过低组12.12%，体质量正常组3.70%，超重组4.42%，肥胖组2.88%，P<0.001）；但各组间 90 d预后不良发生率和卒中复发率差异均无统计学意义（P=0.113，P=0.495）。校正相关混杂因素后，多因素 Logistic回归分析显示，体质量过低是西安地区急性卒中患者90 d死亡的独立危险因素（OR=3.72，95%CI 1.54～9.00，P=0.004），但不是90 d卒中复发和预后不良的独立危险因素（P>0.05）。结论：体质量过低是西 安地区急性卒中患者早期死亡的独立危险因素。
英文摘要:
      To investigate the relationship between body mass index (BMI) and early prognosis in patients with acute stroke in the Xi’an region. Methods: Clinical data of acute stroke patients who were consecutively admitted to 4 tertiary grade A hospitals in the Xi’an area from January 2015 to December 2015 were collected. The clinical characteristics of acute stroke patients with different ranges of BMI (classified as groups underweight, normal weight, overweight, and obese) were compared, and the outcome events (including stroke recurrence, death, and poor prognosis) were followed up for 90 days. Univariate and multivariate Logistic regression analysis was performed to investigate the relationship between BMI and early prognosis in these patients. Results: A total of 2 692 acute stroke patients were enrolled in this study, with a mean age of (63.58± 12.46) years. Follow-up at 90 d revealed significantly higher mortality rate in the low BMI group (12.12% for low vs. 3.70% for normal, 4.42% for overweight, and 2.88% for obese) with statistically significant differences (P<0.001), but there were no statistically significant differences between the groups in poor prognosis rate and stroke recurrence rate at 90 d (P=0.113 and P=0.495). After adjusting for relevant confounders, multivariate Logistic regression analysis showed that low BMI was an independent risk factor for 90 d mortality in acute stroke patient in the Xi’an area (OR=3.72, 95% CI 1.54~9.00, P=0.004) but was not an independent risk factor for stroke recurrence and poor prognosis at 90d (P>0.05). Conclusion: Low BMI was an independent risk factor for early mortality in acute stroke patient in the Xi’an region.
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