| 黄婷婷，朱恒博，何兵，王世红.贫血与热性惊厥的相关性研究[J].神经损伤功能重建,2020,15(8):457-460 |
| 贫血与热性惊厥的相关性研究 |
| Correlation between Anemia and Febrile Convulsion |
| |
| DOI： |
| 中文关键词: 贫血 发热 惊厥 |
| 英文关键词: anemia fever convulsion |
| 基金项目: |
|
| 摘要点击次数: 3077 |
| 全文下载次数: 3228 |
| 中文摘要: |
| 目的：分析贫血与热性惊厥的相关性。方法：采用前瞻性研究，连续纳入2018年10月至2019年4月
就诊于武汉大学人民医院东院儿科的发热患儿，伴有惊厥的纳入惊厥组，不伴有惊厥的纳入对照组。收集
对照组和惊厥组患儿的临床资料如姓名、性别、年龄、发热的病因、热性惊厥的家族史、惊厥发作的类型、红
细胞（RBC）、血红蛋白（Hb）、红细胞压积（HCT）、平均红细胞体积（MCV）、平均红细胞血红蛋白量（MCH）、
平均血红蛋白浓度（MCHC）等；比较2组发热原因、阳性家族史及贫血情况。根据惊厥发作的类型、持续时
间和惊厥发作的次数，进一步将惊厥组分为单纯性热性惊厥组和复杂性热性惊厥组，比较2组的阳性家族
史。结果：本研究共纳入294例发热患儿，其中惊厥组154例（52.4%），对照组140例（47.6%）。2组性别、年 龄、发热病因差异无统计学意义（P＞0.05）。导致发热最常见的疾病为急性上呼吸道感染（63.3%）。惊厥组
中家族史阳性者33例（21.4%），对照组5例（3.6%），差异具有统计学意义（P=0.000）。惊厥组中单纯性热性
惊厥组 121 例（78.6%），家族史阳性 7 例（5.8%）；复杂性热性惊厥组 33 例（21.4%），家族史阳性 26 例 （78.8%），差异有统计学意义（P=0.000）。惊厥组的贫血发生率低于对照组（P=0.010），Hb、HCT、MCV、
MCHC 均高于对照组（均 P＜0.05）；2 组的贫血年龄分布均多见于 12～36 月龄，差异无统计学意义（P= 0.212）。结论：发热伴惊厥患儿中贫血的发生率低于发热不伴惊厥的患儿，且为小细胞低色素贫血。 |
| 英文摘要: |
| To analyze the correlation between anemia and febrile convulsion. Methods: In this
prospective study, we continuously recruited children with fever who visited the pediatric department of Renmin
Hospital of Wuhan University from October 2018 to April 2019. Patients were divided into the control group or
convulsion group based on the absence or presence of convulsions. The patient’s clinical information, including
name, gender, age, temperature, cause of fever, convulsion type, family history, red blood cell (RBC) count, hemoglobin level (Hb), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin
(MCH), and mean corpuscular hemoglobin concentration (MCHC), were collected. The cause of fever, positive
family history of febrile convulsion, and anemia status was compared between the two groups. The convulsion
group patients were further divided into the simple febrile convulsion or complicated febrile convulsion subgroups based on the convulsion type, duration of symptoms, and number of occurrences, and the positive family
history of the two subgroups were compared. Results: A total of 294 children with fever were included, including 154 in the convulsion group (52.4%) and 140 in the control group (47.6%). There was no statistically significant difference in the sex, age, and etiology of fever between the two groups (P>0.05). The most common cause
of fever was acute upper respiratory tract infection (63.3%). There were 33 patients (21.4%) with a positive family history of convulsion in the case group and 5 patients (3.6%) in the control group, and this difference was statistically significant (P=0.000). In the case group, 121 patients (78.6% ) presented with simple febrile convulsion, and 7 (5.8%) of these had a positive family history; 33 patients (21.4%) presented with complicated febrile
convulsion, and 26 (78.8% ) of these had a positive family history. This difference was statistically significant
(P=0.000). The incidence of anemia was lower in the case group than that in the control group (P=0.010). Hb,
HCT, MCV, and MCHC were higher in the case group than that in the control group (all P<0.05). The common
age distribution of anemia in both groups was 12~36 months, and there was no statistically significant difference
(P=0.212). Conclusion: The incidence of anemia is lower in patients with febrile convulsion than that in patients without convulsion, and most cases are microcytic hypochromic anemia. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|