| 武有涛，钟东，杜伟，夏海坚，吴越，杨佳，董康，蒋宏，杨瑞.神经电生理监测在听神经瘤术中面神经功能保护作用的Meta分析[J].神经损伤功能重建,2020,15(6):315-319 |
| 神经电生理监测在听神经瘤术中面神经功能保护作用的Meta分析 |
| Neuroelectrophysiological Monitoring in Protection of Facial Nerve Function in Acoustic Neu⁃roma Surgery: A Meta-Analysis |
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| DOI： |
| 中文关键词: 听神经瘤 神经电生理监测 显微手术 面神经 Meta分析 |
| 英文关键词: acoustic neuroma neuroelectrophysiological monitoring microneurosurgery facial nerve Meta-analysis |
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| 摘要点击次数: 3487 |
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| 中文摘要: |
| 目的：系统评价神经电生理监测辅助显微手术在听神经瘤术中面神经功能保护作用的临床效果。方 法：通过检索PubMed、Cochrane Library、Embase、维普网、中国知网、万方数据库、百度学术等，查找神经电
生理监测辅助显微手术和单纯显微手术在听神经瘤术中面神经功能保护作用的随机对照研究或非随机对
照研究；检索时限为2014年1月至2019年2月。运用STATA 12.0统计软件进行Meta分析。结果：最终共
纳入14篇文献，研究对象共计1247例。Meta分析结果显示：与单纯显微手术治疗相比，神经电生理监测辅
助显微手术在听神经瘤术中的肿瘤全切率更高[OR=1.952, 95%CI(1.364, 2.793), P<0.05]；术中面神经解剖
保留率更优[OR=3.711, 95%CI(2.418, 5.696), P<0.05]；术后随访面神经功能保护率更佳[OR=4.022, 95% CI(2.597, 6.228), P<0.05]；术后面瘫症状明显改善[OR=8.785, 95%CI(4.685, 16.747), P<0.05]。结论：与单纯
显微手术相比，神经电生理监测辅助显微手术在听神经瘤术中肿瘤全切率更高、术中面神经解剖保留率更
高、术后面神经功能保护率更高，且术后面瘫症状明显改善，疗效更好。 |
| 英文摘要: |
| To assess the clinical effect of neuroelectrophysiological monitoring-assisted microsurgery on the protection of facial nerve function in acoustic neuroma surgery. Methods: Using PubMed, Cochrane Library, EMbase, VIP, CNKI, Wan Fang database, and Baidu Scholar, we searched for randomized controlled trials (RCT) and non-randomized controlled trials (nRCT) that studied the protective effect of neuroelectrophysiological monitoring-assisted microsurgery and simple microsurgery on facial nerve function in acoustic
neuroma surgery. The studies retrieved were from January 2014 to February 2019. Meta-analysis was conducted
by STATA12.0 software. Results: Fourteen trials involving 1274 patients were included. The results of meta-analysis showed that, compared to simple microsurgery, neuroelectrophysiological monitoring-assisted microsurgery demonstrated a significantly higher rate of total removal of the tumor [OR=1.952, 95% CI (1.364, 2.793), P<0.05], improved intraoperative anatomical retention rate of the facial nerve [OR=3.711, 95% CI (2.418, 5.696), P<0.05], greater efficiency of the postoperative facial nerve function retention rate [OR=4.022,
95% CI (2.597, 6.228), P<0.05], and improved postoperative facial paralysis symptoms [OR=8.785, 95% CI (4.685, 16.747), P<0.05]. Conclusion: Compared to simple microsurgery, neuroelectrophysiological monitoring-assisted microsurgery can effectively improve the rate of total tumor removal, intraoperative anatomical retention rate of the facial nerve, postoperative protective rate of nerve function, and postoperative symptoms of
facial paralysis |
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