| 周凌云
，郭晓雪
，苏畅
，刘微
，吴秀亭
，王家运
，刘铁镌
，栗雪梅
，赵明
，纪晓杰.眶内电针治疗Fisher综合征所致眼肌麻痹临床观察[J].神经损伤功能重建,2020,15(4):204-206 |
| 眶内电针治疗Fisher综合征所致眼肌麻痹临床观察 |
| Clinical Observation of Intra-Orbital Electroacupuncture against Miller Fisher Syndrome Oph⁃thalmoplegia |
| |
| DOI： |
| 中文关键词: 眶内电针 Fisher综合征 眼肌麻痹 |
| 英文关键词: intra-orbital electroacupuncture Miller Fisher Syndrome ophthalmoplegia |
| 基金项目:国家自然科学基金
（No. 81674052）；
黑龙江中医药科
研项目（No. ZHY1 2-W031） |
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| 中文摘要: |
| 目的：回顾分析眶内电针（IEA）治疗Fisher综合征（MFS）眼肌麻痹疗效及MFS眼肌麻痹患者的临床
特点。方法：收集接受IEA治疗的MFS患者27例的资料，对一般资料、受累颅神经、感染情况、治疗前后最
大复视角度、治疗及恢复情况等进行回顾分析。结果：患者从发病到开始接受 IEA 治疗的平均时间为
（31.04±46.23）d，接受治疗后达到临床痊愈的平均天数为（33.67±21.96）d。临床痊愈（无复视致残）24 例 （88.9%）。治疗后，左眼和右眼的最大复视角度均较治疗前显著降低（P＜0.01）。MFS眼肌麻痹特点：100%
患者有外展神经病变，其中11.1%为单侧病变，88.9%为双侧受累；37.0%合并 III、VI对颅神经麻痹，无孤立
的III或 IV对颅神经麻痹患者。70.3%有感染史；11.1%伴发高血压、7.4%伴发高脂血症、3.7%伴发2型糖尿
病。22.2%伴有Bell征，双侧受累4例，单侧受累2例。25.9%眼睑下垂，双侧受累5例，单侧受累2例。3.7%
伴有双侧瞳孔散大。结论：IEA治疗可加快MFS眼肌麻痹症状恢复，MFS眼肌麻痹的临床特点可提示临床
诊断。 |
| 英文摘要: |
| To review the effectiveness of intra-orbital electroacupuncture (IEA) in the treatment of
Miller Fisher Syndrome (MFS) ophthalmoplegia and the clinical characteristics of MFS ophthalmoplegia. Meth⁃
ods: We reviewed the medical records of 27 MFS ophthalmoplegia patients who received IEA therapy and retrospectively analyzed the general data, infection status, maximum diplopia deviation before and after treatment,
and treatment and recovery status. Results: The mean time from onset to the start of IEA treatment in patients
was (31±46.23) days, and the mean time from treatment to recovery was (33.67±21.96) days. The number of patients clinically cured (no diplopia) was 24 (88.9%). After treatment, the average maximum diplopia deviation of
the left and right eye was significantly decreased (P<0.01). Abducens nerve (CN VI) paralysis was seen in 100%
of patients with 11.1% being unilaterally affected and 88.9% bilaterally affected. Combined CN III and VI paralysis occurred in 37.0% of patients, and isolated CN III and CN IV paralysis was not seen. Infection was seen in
70% of patients. Concomitant disease included hypertension (11.1%), hyperlipemia (7.4%), and type 2 diabetes
(3.7%). Bell’s phenomenon was seen in 22.2% of patients including 4 bilateral and 2 unilateral cases. Ptosis occurred in 25.9% of patients including 5 bilateral and 2 unilateral cases. Bilateral pupil dilation was seen in 3.7%
of patients. Conclusion: IEA therapy may accelerate the recovery from MFS ophthalmoplegia, and the clinical
features of MFS ophthalmoplegia may aid diagnosis. |
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