| To investigate the clinical characteristics of Parkinson's disease (PD) with anxiety
and explore its risk factors. Methods: A cross-sectional study of PD patients was carried out in the
outpatient department of our hospital and Beijing Tiantan Hospital. The clinical characteristics such as age of
onset, disease duration, initial symptoms, modified H-Y stages, MDS-UPDRS-Ⅲ, combination with restless
legs syndrome (RLS), and Becker anxiety scale scores were collected. The incidence and influencing factors
of anxiety in PD were analyzed by multivariate logistic method. Results: A total of 263 PD patients were
included; 65 patients (24.7% ) had anxiety, and 36 of these patients were female. Longer course of disease,
higher H-Y stages and MDS-UPDRS- Ⅲ scores, and combination with RLS were positively related with
anxiety (P˂0.05), but there was no significant correlation between anxiety and the age of onset, education
level, or initial symptoms (P ˃ 0.05). Conclusion: Being female, longer duration of disease, more severe
motor function, and combination with RLS are risk factors for PD with anxiety. |