| 孙金梅，陈彬，许春伶，李尧，张拥波.短暂性全面性遗忘的临床诊治分析[J].神经损伤功能重建,2019,14(8):392-394 |
| 短暂性全面性遗忘的临床诊治分析 |
| Clinical Analysis of Transient Global Amnesia |
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| DOI： |
| 中文关键词: 短暂性全面性遗忘，低灌注，应激 |
| 英文关键词: transient global amnesia hypo-perfusion stress |
| 基金项目:国家自然科学基金
（No. 81801334）
首都医科大学附属
北京友谊医院院启
动课题（No. yyqdkt
2017-13） |
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| 中文摘要: |
| 目的：总结分析短暂性全面性遗忘的危险因素、发病机制、临床表现、辅助检查及治疗方法，以其加深
对该病的认识。方法：收集短暂性全面性遗忘患者15例的临床资料进行分析，并结合文献回顾。结果：15
例患者中女性占66.7%；年龄56～85岁，平均年龄67.1岁；3例并发焦虑、抑郁。15例均以突发记忆丧失为主
诉，同时伴随头晕、头痛等症状；3例发病前有情绪激动诱因；4例并发心率失常，脑电图均无异常尖波、棘波
等；5例头颅CTA提示大脑后动脉存在变异或狭窄。全组头颅核磁均未检测到DWI异常信号。治疗上均给
予抗血小板聚集、改善循环等治疗；2例复发。结论：短暂性全面性遗忘主要表现新记忆的形成障碍，是一种
临床过程良性的疾病，血管因素、低灌注、情绪应激均参与该病的发病过程。 |
| 英文摘要: |
| To explore the clinical features, imaging manifestation, auxiliary examination, and
treatment of transient global amnesia and gain deeper insight about this condition. Methods: The clinical data of
15 patients with transient global amnesia were collected and analyzed and discussed retrospectively. Results:
Among the 15 patients, 67% were female, and the age range was 56~85 years with an average age of 67.1 years;
3 patients experienced simultaneous anxiety and depression. All 15 patients complained mainly of sudden
memory loss, and this was accompanied by dizziness, headache, and other symptoms; 3 patients had emotional
triggers before the onset of disease; 4 patients were found to have concurrent arrhythmias, and no abnormal
spikes were found in the EEG. CTA of 5 patients indicated variation or narrowing of the posterior cerebral artery.
No abnormal signal of DWI was detected by MRI in all patients. Antiplatelets and circulation enhancers were
given to all patients, and 2 patients relapsed. Conclusion: Transient global amnesia presents mainly as the
inhibition of new memory formation; it is a benign condition. Vascular factors, hypo-perfusion, and emotional
stress are all involved in its pathogenesis. |
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