文章摘要
高金颖 ，胡蓉 ，金迪 ，张绿明 ，赵静 ，马瑞 ，邱石.SOAR量表和ASTRAL量表评分对急性缺血性卒中患者1年不良预后的预测功能评价[J].神经损伤功能重建,2019,14(8):383-385
SOAR量表和ASTRAL量表评分对急性缺血性卒中患者1年不良预后的预测功能评价
Comparison of the SOAR Score and ASTRAL Score in 1 Year Poor Prognosis in Patients withAcute Ischemic Stroke
  
DOI：
中文关键词: 急性缺血性卒中  不良预后  SOAR量表  ASTRAL量表
英文关键词: acute ischemic stroke  poor prognosis  SOAR  ASTRAL
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作者单位
高金颖1a ，胡蓉2 ，金迪1b ，张绿明1b ，赵静1b ，马瑞1b ，邱石1b 1. 航 天 中 心 医 院 （北京大学航天临 床医学院）a.健康管 理部，b.神经内科 2. 首都医科大学基 础医学院临床医学 专业 
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中文摘要:
      目的：探讨SOAR和ASTRAL评分对急性缺血性卒中（AIS）患者1年不良预后的预测价值。方法：纳 入AIS患者807例，收集临床基线资料，同时应用SOAR和ASTRAL量表进行评分，并进行1年随访。以患 者1年时出现死亡或功能残障（mRS≥3分）作为不良结局事件。通过受试者工作特征曲线下面积（AUC）比 较 2 个量表的预测价值。结果：最终纳入 AIS 患者 772 例进行数据分析，1 年随访出现不良结局 196 例 （25.4%），其中死亡68例（8.8%）。SOAR和ASTRAL量表预测AIS患者1年不良预后结局的AUC值分别为 0.739和0.860（均P＜0.001），差异有统计学意义（P＜0.001）；SOAR和ASTRAL量表预测AIS患者1年死亡 结局的AUC值分别为0.755和0.809，差异有统计学意义（P＜0.001）。结论：应用SOAR和ASTRAL量表能 够较好地对AIS人群的1年不良预后进行预测；ASTRAL量表的预测能力优于SOAR量表。
英文摘要:
      To investigate the predictive value of SOAR and ASTRAL scores for one-year poor prognosis in patients with acute ischemic stroke (AIS). Methods: A total of 807 AIS patients were enrolled. Clinical baseline data were collected and scored with SOAR and ASTRAL scores. A prospective cohort follow-up study was performed for 1 year. The patient had a death or functional disability at 1 year [modified Rankin score (mRS) ≥3 points] as an adverse outcome event. The area under the receiver operating characteristic curve (AUC) was used to compare the predicted values of the two scales. Results: A total of 772 AIS patients' data were collected in the study. There were 196 (25.4% ) adverse outcomes at 1 year follow-up, including 68 deaths (8.8%). The AUR values for the 1-year adverse outcome of the AIS patients predicted by the SOAR and ASTRAL scales were 0.739, 0.860, respectively (both P＜0.001). Further comparisons were made between the two scales, the difference was statistically significant (P＜0.001). The 1 year mortality outcome of AIS patients was further analyzed by two scales. The AUC values were 0.755, 0.809 (both P＜0.001). Further comparison between the two groups was statistically significant (P＜0.001). Conclusion: The SOAR and ASTRAL scales can predict the 1-year adverse prognosis of AIS population. The ASTRAL scale is superior to SOAR scale in predicting 1-year adverse outcomes and death events in patients with AIS.
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