| 王静云，姜雪松，董一，胡日光.58 例贫血并发脑梗死患者的临床特征[J].神经损伤功能重建,2019,14(5):225-227 |
| 58 例贫血并发脑梗死患者的临床特征 |
| Clinical Features of 58 Cases of Anemia Complicated with Cerebral Infarction |
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| DOI： |
| 中文关键词: 贫血 脑梗死 临床特征 预后 相关性 |
| 英文关键词: anemia cerebral infarction clinical features prognosis correlation |
| 基金项目: |
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| 中文摘要: |
| 目的：观察贫血并发脑梗死患者的临床特征，分析脑梗死患者贫血与预后的相关性。方法：回顾性分
析180 例脑梗死患者临床资料。根据患者入院时是否存在贫血分为贫血组（n=58）和非贫血组（n=122），比
较2 组临床资料差异。再根据患者发病后6 月时改良Rankin 量表（mRS）评分将其分为预后不良组（mRS＞2
分，n=45）和预后良好组（mRS≤2 分，n=135），分析贫血与预后的相关性。结果：贫血并发脑梗死贫血程度多
为中度，类型多为小细胞低色素性贫血；出现运动、语言、意识障碍症状患者比例较高；病变多位于前循环分
布区，病灶以多发性梗死灶为主。与非贫血组比较，贫血组患者年龄、入院时NIHSS评分、患慢性肾脏病比
例大于非贫血组（P＜0.05）。预后不良组与预后良好组年龄、入院NIHSS评分、糖尿病、心房纤颤、复发性脑
梗死、贫血等因素差异有统计学意义（P＜0.05）。Logistic 回归分析显示，入院NIHSS 评分、贫血、复发性脑
梗死是脑梗死患者预后不良的独立预测因子（P＜0.05）。结论：贫血与脑梗死患者年龄、神经功能缺损严重
程度及慢性肾病发生率密切相关，入院NIHSS评分较高、伴发贫血、复发性脑梗死的患者预后较差。 |
| 英文摘要: |
| To observe the clinical features of anemia complicated with cerebral infarction and analyze
the correlation between anemia and prognosis in patients with cerebral infarction. Methods: The clinical data
of 180 patients with cerebral infarction were retrospectively analyzed. Clinical features of anemia complicated
with cerebral infarction were analyzed. Based on the presence of anemia at admission, patients were divided into
the anemia group (n=58) and non-anemia group (n=122), and the clinical data of the two groups were compared.
According to the modified Rankin scale (mRS) score at 6 months after onset, patients were additionally divided
into the poor prognosis group (mRS>2 points, n=45) and good prognosis group (mRS≤2 points, n=135). The
correlation between anemia and prognosis was analyzed. Results: The degree of anemia in cerebral infarction
combined with anemia was mostly moderate, and the type was mostly microcytic hypochromic anemia. The proportion
of patients with motor, language, and consciousness disorders was relatively high. Lesions were mostly
located in the anterior circulation of the brain and were mostly multiple infarcts. The age, NIHSS score at admission,
and proportion of patients with chronic kidney disease in the anemia group were significantly greater than
those in the non-anemia group (P<0.05). There were significant differences between the poor prognosis group
and good prognosis group in age, NIHSS score at admission, diabetes, atrial fibrillation, recurrent cerebral infarction,
anemia, and other factors (P<0.05). Logistic regression analysis showed that NIHSS score at admission, anemia,
and recurrent cerebral infarction were independent predictors for poor prognosis in patients with cerebral infarction
(P<0.05). Conclusion: Anemia is closely related to the age, severity of neurological deficit, and incidence
of chronic kidney disease of patients with cerebral infarction. Patients with a high NIHSS score at admission,
anemia, and recurrent cerebral infarction display a higher proportion of poor prognosis. |
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