| 胡苏华，彭伟，许辉，吕育玲，乔向亮.侧支循环与急性脑梗死机械取栓疗效及转归的相关性分析[J].神经损伤功能重建,2018,13(11):541-543 |
| 侧支循环与急性脑梗死机械取栓疗效及转归的相关性分析 |
| Correlation Analysis of Collateral Circulation and Curative Effect and Outcomes of AcuteCerebral Infarction After Mechanical Thrombectomy |
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| DOI： |
| 中文关键词: 侧支循环 急性脑梗死 机械取栓 |
| 英文关键词: collateral circulation acute cerebral infarction mechanical thrombectomy |
| 基金项目:随州市卫计委医学科研项目（2016SZ32015） |
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| 中文摘要: |
| 目的：研究侧支循环与急性脑梗死患者机械取栓治疗疗效及临床转归的相关性。方法：回顾性分析
31 例进行机械取栓治疗的急性脑梗死患者，分级评估患者的侧支循环状态，并分为侧支循环良好组与侧支
循环不良组，根据NIHSS评分判定疗效，以90 d 的mRS评分判定临床转归并分为转归良好（0～2 分）和转归
不良（3～5 分），采用多因素Logistic 回归分析研究侧支循环对机械取栓治疗临床转归的影响。结果：侧支循
环良好组与侧支循环不良组基线NIHSS 评分对比差异无统计学意义（P=0.055），15 d NIHSS 评分对比有显
著性差异（P=0.004）；31 例患者中临床转归良好17 例，转归不良14 例，基线NIHSS 评分（P=0.044）和侧支循
环评分（P=0.021）是临床转归的重要影响因素。结论：进行机械取栓治疗的急性脑梗死患者中，侧支循环良
好者更易获得神经功能改善，侧支循环评分及基线NIHSS评分与临床转归可能存在一定相关性。 |
| 英文摘要: |
| To explore the possible relation between collateral circulation and curative effects and
clinical outcomes in patients with acute cerebral infarction after mechanical thrombectomy. Methods: A total of
31 patients with acute cerebral infarction who received mechanical thrombectomy were retrospectively analyzed.
The status of collateral circulation of patients was hierarchically evaluated to divide patients into the good
collateral circulation group and poor collateral circulation group. The curative effects were determined according
to NIHSS score. The clinical outcomes, such as good outcome (0～2 points) or poor outcome (3～5 points), were
determined based on the mRS score at day 90. Multiple Logistic regression analysis was used to study the effects
of collateral circulation on the clinical outcome after mechanical thrombectomy. Results: There was no
statistically significant difference in the baseline NIHSS score between the good collateral circulation group and
poor collateral circulation group (P=0.055), but there was a significant difference in NIHSS score between the
two groups at day 15 (P=0.004). Among the 31 patients, 17 cases had good outcomes and 14 cases had poor
outcomes. Baseline NIHSS score (P=0.044) and collateral circulation score (P=0.021) were important
influencing factors of clinical outcomes. Conclusion: Among patients with acute cerebral infarction who
received mechanical thrombectomy, those with good collateral circulation are more likely to achieve
improvement of neurological function. Collateral circulation score and baseline NIHSS score may have a certain
correlation with clinical outcomes. |
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