| 陈先海，徐高峰，白晓斌，谢万福.动脉粥样硬化与颅内动脉瘤破裂的相关性研究[J].神经损伤功能重建,2018,13(3):120-121 |
| 动脉粥样硬化与颅内动脉瘤破裂的相关性研究 |
| Correlation between Atherosclerosis and Rupture of Intracranial Aneurysms |
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| DOI： |
| 中文关键词: 动脉粥样硬化 颅内动脉瘤 回顾性分析 |
| 英文关键词: atherosclerosis intracranial aneurysms retrospective analysis |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨动脉粥样硬化（AS）与颅内动脉瘤破裂的相关性。方法：颅内动脉瘤患者120例纳入研究，
根据动脉瘤是否破裂分为破裂组99例和未破裂组21例，对其临床及随访资料进行回顾性分析，χ
2
检验分析
颅内动脉瘤发生破裂的相关危险因素及AS与颅内动脉瘤的易感性。结果：颅内动脉瘤是否破裂与患者性
别、个人饮酒和吸烟史、心脑血管疾病既往史、颅内动脉瘤发生部位和颅内动脉瘤的大小有关（P＜0.05）。
颅内动脉瘤患者并发AS与患者具有动脉狭窄、早期的血管内皮损伤及患者体内炎性反应有关（P＜0.05）；
多因素Logistic回归分析结果显示，AS是发生颅内动脉瘤破裂的主要影响因素之一。结论：颅内动脉瘤是
否破裂与患者性别、个人饮酒和吸烟史、心脑血管疾病既往史、颅内动脉瘤的发生部位和大小有关；AS可能
与颅内动脉瘤破裂具有一定的相关性。 |
| 英文摘要: |
| To investigate the correlation between atherosclerosis (AS) and intracranial aneurysm
rupture. Methods: One hundred and twenty cases with intracranial aneurysm were included, which were
divided into ruptured group (n=99) and unruptured group (n=21). Clinic data was collected and retrospectively
analyzed. The related risk factors of intracranial aneurysms rupture were analyzed by χ 2 test. The correlation
between AS and intracranial aneurysm rupture was analyzed. Results: The gender, personal history of drinking
and smoking, history of cardiovascular and cerebrovascular diseases, and the sites and the size of intracranial
aneurysms were the risk factors for intracranial aneurysm rupture (P<0.05). AS was more likely to be detected in
intracranial aneurysm patients with arteriostenosis, early vascular endothelial injury and inflammatory response
(P<0.05). Multivariate logistic regression analysis results showed that AS was one of the main factors influencing
the rupture of intracranial aneurysms. Conclusion: The gender, personal history of drinking and smoking,
history of cardiovascular and cerebrovascular diseases, and the site and the size of intracranial aneurysms were
the risk factors for intracranial aneurysm rupture. AS may be associated with intracranial aneurysm rupture. |
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