文章摘要
何浩楠，姚晓东.持续性姿势知觉性头晕的亚型及其临床特征[J].神经损伤功能重建,2024,(知网首发):
持续性姿势知觉性头晕的亚型及其临床特征
Subtypes and Clinical Features of Persistent Postural-Perceptual Dizziness
  
DOI：
中文关键词: 持续性姿势知觉性头晕  亚型  因子分析  聚类分析
英文关键词: persistent postural-perceptual dizziness, subtypes, factor analysis, cluster analysis
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作者单位
何浩楠，姚晓东 山西医科大学附属 山西省人民医院全 科医疗科 
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中文摘要:
      目的：探索持续性姿势知觉性头晕（persistent postural-perceptual dizziness，PPPD）可能存在的亚型及 其临床特征。方法：选取2023年5月～2023年12月就诊于山西省人民医院眩晕门诊的PPPD患者106例， 收集患者一般资料及临床资料；接诊时采取问卷调查的形式完成新泻 PPPD 问卷（NPQ）、眩晕障碍量表 （DHI）、医院焦虑抑郁量表（HADS）、特质焦虑量表（STAI）评分；对量表内容进行因子分析，随后根据因子分 析的结果进行聚类分析，同时对每组患者进行特征分析。结果：因子分析揭示了3个因子，主动运动因子 （32.82%）、视觉刺激因子（14.80%）、直立姿势因子（10.97%）。聚类分析揭示了3个亚型，视觉刺激优势亚型 （25例）、姿势控制优势亚型（24例）、主动运动优势亚型（57例）。3个亚型在年龄、职业、家族头疼史上有着 显著差异（P＜0.05）。视觉刺激优势亚型年龄小、有明显的家族头疼史，职业以银行/超市职员为主；姿势控 制优势亚型的职业以公务员、教师为主；主动运动优势亚型的职业以工人、农民为主。其他临床数据差异无 统计学意义（P＞0.05）。结论：PPPD最常见的加重因素是主动运动因素；可以分为3个亚型，各个亚型在年 龄、职业、家族头疼史上有着显著特点。
英文摘要:
      To explore the possible subtypes and clinical characteristics of persistent postural-perceptual dizziness(PPPD). Methods: A total of 106 patients diagnosed with PPPD were selected from the Shanxi People’s Hospital between May 2023 and December 2023. General and clinical data of the patients were collected; upon admission, questionnaires including the Niigata PPPD Questionnaire(NPQ), Dizziness Handicap Inventory(DHI), Hospital Anxiety and Depression Scale(HADS), and State-Trait Anxiety Inventory(STAI) were administered. Factor analysis was conducted on the scale items, followed by cluster analysis based on the results of the factor analysis, with characteristic analysis performed for each patient group. Results: Factor analysis revealed three factors, named active motor factor(32.82% ), visual stimulation factor(14.80% ), and upright position factor(10.97% ). Cluster analysis identified three subtypes: visual stimulation-dominant subtype(n=25), posture control-dominant subtype(n=24), and active motor-dominant subtype(n=57). There were statistically significant differences in age, occupation, and family history of headaches among the three subtypes(P<0.05). The visual stimulation-dominant subtype patients had younger ages, with a notable family history of headache, and worked primarily as bank/supermarket clerks; the posture control-dominant subtype mainly consisted of civil servants, teachers; while the active motor-dominant subtype included predominantly workers, farmers. No statistically significant differences were found in other clinical data(P>0.05). Conclusion: The most common exacerbating factor for PPPD is active movement; it can be divided into three subtypes, each with significant characteristics in terms of age, occupation, and family history of headaches.
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