| 成小菲
，杨媛媛
，梁春婷
，王德花
，李思慧
，姚筱朵
，冯露叶
，汤继芹.虚拟现实技术对脑卒中患者认知功能影响的Meta分析[J].神经损伤功能重建,2025,(知网首发): |
| 虚拟现实技术对脑卒中患者认知功能影响的Meta分析 |
| Effect of Virtual Reality Technology on Cognitive Function in Stroke Patients: a Meta-analysis |
| |
| DOI： |
| 中文关键词: 脑卒中 虚拟现实技术 认知功能 日常生活活动能力 Meta分析 |
| 英文关键词: stroke virtual reality technology cognitive function activities of daily living Meta-analysis |
| 基金项目:山东省中医药科技
发展项目（针刺与重
复经颅磁刺激治疗
脑中风后轻度认知
功能障碍的循证研
究，No. 2017-011）；
山东省老年医学学
会基金（针刺与重
复经颅磁刺激治疗
老年轻度抑郁症的
循证研究，No. LKJ
GG2021Z018）；山
东中医药大学科研
创新团队基金资助
项目（经方治疗重
大疾病作用机理与
疗效评价科研创新
团队，No. 220316） |
|
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| 中文摘要: |
| 目的：系统评价虚拟现实技术对脑卒中患者认知功能的影响。方法：计算机检索国内外多个数据库中
关于虚拟现实技术干预脑卒中后认知障碍患者的随机对照试验，检索时限为建库至2025年1月7日。使用
Cochrane 协作网中的偏倚风险评估工具和物理治疗证据数据库（PEDro）量表评估文献质量，采用 RevMan5.4.1软件进行数据分析。结果：最终纳入14篇文献，涉及723例患者。纳入的文献均为高质量文献，PEDro量表评分6～10分。Meta分析结果显示，虚拟现实技术可以改善脑卒中认知障碍患者蒙特利尔认知评估
（MoCA）评分[MD=2.53, 95%CI (0.82, 4.24), P=0.004]、简易智能精神状态量表（MMSE）评分[MD=1.68, 95%
CI (1.12, 2.24)，P＜0.00001]、P300潜伏期[MD=－25.48, 95%CI (－38.99, －11.96), P=0.0002]、P300波幅[MD=
0.72, 95%CI (0.14, 1.30), P=0.02]、Barthel 指数或改良 Barthel 指数（BI 或 MBI）评分[MD=5.14, 95%CI (3.25,
7.03), P＜0.00001]；但对连线测试 TMT-A 评分[MD =－12.47, 95%CI (－27.16, 2.23), P=0.10]、TMT-B 评分效
果不显著[MD = －44.35, 95%CI (－117.45, 28.74), P=0.23]。结论：虚拟现实技术可以改善脑卒中患者的认知
功能和日常生活活动能力。 |
| 英文摘要: |
| To systematically evaluate the impact of virtual reality (VR) technology on cognitive
function in stroke patients. Methods: A computer-based search was conducted across multiple domestic and
international databases for randomized controlled trials (RCTs) investigating VR interventions in patients with
post-stroke cognitive impairment. The search period spanned from the inception of the databases to January 7,
2025. The Cochrane Collaboration's Risk of Bias tool and the Physiotherapy Evidence Database (PEDro) scale
were employed to assess the quality of the included studies. Data analysis was performed using RevMan 5.4.1
software. Results: A total of 14 studies, involving 723 patients, were ultimately included. All included studies
were of high quality, with PEDro scale scores ranging from 6 to 10. Meta-analysis results indicated that VR
technology significantly improved the Montreal Cognitive Assessment (MoCA) score [MD=2.53, 95% CI (0.82,
4.24), P=0.004], the Mini-Mental State Examination (MMSE) score [MD=1.68, 95% CI (1.12, 2.24), P<0.00001],
the P300 latency [MD=－25.48, 95% CI (－38.99, －11.96), P=0.0002], the P300 amplitude [MD=0.72, 95% CI
(0.14, 1.30), P=0.02], and the Barthel Index or Modified Barthel Index (BI or MBI) score [MD=5.14, 95% CI
(3.25, 7.03), P<0.00001] in stroke patients with cognitive impairment. However, no significant effects were
observed on the Trail Making Test Part A (TMT-A) score [MD=－12.47, 95% CI (－27.16, 2.23), P=0.10] or the
TMT-B score [MD=－ 44.35, 95% CI (－ 117.45, 28.74), P=0.23]. Conclusion: VR technology can improve
cognitive function and activities of daily living (ADL) abilities in stroke patients. |
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