文章摘要
郭英 ，陈静 ，梁玲 ，李红丽 ，李彪 ，梁宝 ，向东方.幻听与抑郁发作患者非自杀性自伤行为的关联性研究[J].神经损伤功能重建,2023,(知网首发):
幻听与抑郁发作患者非自杀性自伤行为的关联性研究
Relationship between Auditory Hallucinations and Non-suicidal Self-injury behaviors inPatients with Depressive Episodes
  
DOI：
中文关键词: 非自杀性自伤行为  幻听  抑郁发作
英文关键词: non-suicidal self-injury behaviors  hallucination  depressive episode
基金项目:湖北省卫生健康委 员会科研项目（基 于锂同位素对女性 双相情感障碍患者 锂盐疗效-副作用 差异性的研究 No. WJ2023M141）
作者单位
郭英1 ，陈静1 ，梁玲2 ，李红丽1 ，李彪1 ，梁宝1 ，向东方1 1. 武汉市精神卫生 中心、武汉市心理 医院 2. 华中科技大学公 共卫生学院儿少卫 生与妇幼保健学系 
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中文摘要:
      目的：探究抑郁发作患者非自杀性自伤行为（non-suicidal self-injury，NSSI）检出特征及其与幻听之间 的关系。方法：采用随机整群抽样的方法纳入473例抑郁发作患者，使用一般人口学问卷、渥太华自伤量表 和精神症状评定量表中文版（Psychotic Symptom Rating Scales，PSYRATS）进行调查，分析NSSI与幻听症状 的关系。结果：抑郁发作患者NSSI检出率为40.6%，NSSI在年龄、性别、病程、职业、受教育程度、婚姻状况、 家族史、诊断分类、吸烟史、饮酒史和有无幻听等方面差异有统计学意义（均P＜0.05）。有幻听症状的男性和 女性抑郁发作患者NSSI检出率分别为42.9%和67.6%，无幻听症状分别为19.8%和42.1%，差异均有统计学 意义（均P＜0.05）。在诊断分类上，单相抑郁发作组中有无幻听症状的NSSI检出率差异有统计学意义（P＜ 0.05），其中男性和女性NSSI检出率差异均有统计学意义（P＜0.05）；在双相抑郁发作中有无幻听症状的NSSI 检出率差异有统计学意义（P＜0.05），但仅在女性中 NSSI 检出率差异有统计学意义（P＜0.05）。幻听与 NSSI最常自伤部位有一定关联性（P＜0.05）。幻听与NSSI行为特征值二元Logistic回归显示：在调整了性 别、年龄、职业等因素后，幻听与NSSI行为呈显著正相关（OR=1.04，95%CI 1.01～1.08，P＜0.05）。结论：抑郁 发作患者幻听症状与NSSI行为呈正相关。
英文摘要:
      To explore the detected characteristics of non-suicidal self-injury (NSSI) behaviors and their relationship with auditory hallucination in patients with depressive episodes. Methods: A total of 473 patients with depressive episodes were enrolled by random cluster sampling. The general demographic questionnaire, the Ottawa Self-Injury Scale and the Chinese version of the Psychiatric Symptom Rating Scale (PSYRATS) were used to analyze the relationship between NSSI and auditory hallucination symptoms. Results: The detection rate of NSSI in patients with depressive episodes was 40.6% . NSSI had statistically significant differences in age, sex, course of disease, occupation, education level, marital status, family history, diagnostic classification, smoking and drinking history, and presence of auditory hallucinations (P<0.05). The prevalence of NSSI was 42.9% and 67.6% in men and women with auditory hallucinations, and 19.8% and 42.1% in men and women without auditory hallucinations; the differences were statistically significant (P<0.05). In terms of diagnostic classification, the detection rate of NSSI between patients with and without auditory hallucinations in the unipolar depressive episode group was significantly different (P<0.05), which was significant different both in males and females (P<0.05). The detection rate of NSSI between patients with and with auditory hallucination in the group of bipolar depressive episodes was significantly different (P<0.05), which was significant different only in females (P<0.05). Auditory hallucinations were associated with the most frequent sites of NSSI (P<0.05). After adjustment of for gender, age and occupation, binary Logistic regression showed that there was a significant positive correlation between auditory hallucinations and NSSI behavior characteristic values (OR=1.04, 95%CI 1.01～1.08, P<0.05). Conclusion: Auditory hallucinations in patients with depressive episodes is positively correlated with NSSI behavior.
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